Evidence map›Paper›PMID 33466278›Full record

ReviewCells2021

A New Option for the Treatment of Intrahepatic Cholangiocarcinoma: Percutaneous Hepatic Perfusion with CHEMOSAT Delivery System.

Pier Francesco Ferrucci, Emilia Cocorocchio, Guido Bonomo, Gianluca Maria Varano, Paolo Della Vigna, Franco Orsi

Open access · goldAbstract readReview
In one paragraph

Review in Cells, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
2.1field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 11 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Pier Francesco FerrucciTumor Biotherapy Unit, Department of Experimental Oncology, European Institute of Oncology, IRCCS, 20141 Milan, Italy.ORCID 0000-0001-6255-5851
Emilia CocorocchioHematoncology Division, European Institute of Oncology, IRCCS, 20141 Milan, Italy.ORCID 0000-0003-1184-6426
Guido BonomoInterventional Radiology Division, European Institute of Oncology, IRCCS, 20141 Milan, Italy.
Gianluca Maria VaranoInterventional Radiology Division, European Institute of Oncology, IRCCS, 20141 Milan, Italy.
Paolo Della VignaInterventional Radiology Division, European Institute of Oncology, IRCCS, 20141 Milan, Italy.ORCID 0000-0002-8523-9226
Franco OrsiInterventional Radiology Division, European Institute of Oncology, IRCCS, 20141 Milan, Italy.
European Institute of Oncology · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Liver metastases are a major management problem; since they occur in tumors of different origin, they are often multiple, difficult to visualize and can lie dormant for many years. Patients with liver metastases usually die of their disease, mostly due to liver failure, since systemic treatments are unable to eradicate micro-metastasis, and interventional loco-regional procedures cannot treat all existing ones. Cholangiocarcinoma (CCA) is the second most common primary liver tumor, showing a poor overall prognosis. When resection is not possible, treatment options include tumor-focused or local ablative therapy, organ-focused or regional therapy and systemic therapy. We reviewed available loco-regional therapeutic options, with particular focus on the CHEMOSAT

Indexed as

Drug Delivery SystemsAnimalsBile Duct NeoplasmsCholangiocarcinomaClinical Trials as TopicHumansLiverPerfusionintrahepatic cholangiocarcinomaliver metastasispercutaneous hepatic perfusionregional therapy

Identifiers

PMID33466278
PMCPMC7824743
OpenAlexW3119400669

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.