Evidence map›Paper›PMID 33465812›Full record

ArticleJournal of clinical periodontology2021

Ultrasonographic tissue perfusion analysis at implant and palatal donor sites following soft tissue augmentation: A clinical pilot study.

Lorenzo Tavelli, Shayan Barootchi, Jad Majzoub, Hsun-Liang Chan, William V Giannobile, Hom-Lay Wang, Oliver D Kripfgans

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of clinical periodontology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
38citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

38 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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  3. Cyanoacrylate Adhesive in Free Gingival Graft Healing: A Digital and Microcirculatory Randomized Clinical Trial.Journal of esthetic and restorative dentistry : official publication of the American Academy of Esthetic Dentistry ... [et al.] · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Lorenzo TavelliDepartment of Periodontics & Oral Medicine, University of Michigan School of Dentistry, Ann Arbor, MI, USA.ORCID 0000-0003-4864-3964
Shayan BarootchiDepartment of Periodontics & Oral Medicine, University of Michigan School of Dentistry, Ann Arbor, MI, USA.ORCID 0000-0002-5347-6577
Jad MajzoubDepartment of Periodontics & Oral Medicine, University of Michigan School of Dentistry, Ann Arbor, MI, USA.
Hsun-Liang ChanDepartment of Periodontics & Oral Medicine, University of Michigan School of Dentistry, Ann Arbor, MI, USA.ORCID 0000-0001-5952-0447
William V GiannobileDepartment of Periodontics & Oral Medicine, University of Michigan School of Dentistry, Ann Arbor, MI, USA.ORCID 0000-0002-7102-9746
Hom-Lay WangDepartment of Periodontics & Oral Medicine, University of Michigan School of Dentistry, Ann Arbor, MI, USA.ORCID 0000-0003-4238-1799
Oliver D KripfgansBiointerfaces Institute and Department of Biomedical Engineering, College of Engineering, Ann Arbor, MI, USA.

Funding

Michigan Institute for Clinical and Health Research (MCHR)UL1TR000433 · NCATS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI MASHOUR, GEORGE ALEXANDER · 2012 to 2016
$49.9M
Quantitative Estimation of Periodontal Inflammation and Tissue Destruction with High-Resolution Ultrasound-Based Imaging - Admin SuppR21DE029005 · NIDCR · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI KRIPFGANS, OLIVER D · 2020 to 2021
$466k
Point of Care, High Resolution and 3-Dimensional Ultrasonography for Diagnosing Peri-Implant Bone LossR21DE027765 · NIDCR · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI CHAN, HSUN-LIANG, KRIPFGANS, OLIVER D · 2019 to 2020
$412k
NCATS NIH HHS UL1 TR000433NCATS NIH HHS UL1TR000433NIDCR NIH HHS R21 DE027765NIDCR NIH HHS R21 DE029005
6 · The paper itself

Abstract

aimTo describe the application of power Doppler Ultrasonography (US) for evaluating blood flow at implant and palatal donor sites following soft tissue augmentation with the connective tissue graft (CTG). MATERIALS AND

methodsFive patients exhibiting a peri-implant soft tissue dehiscence received treatment with a coronally advanced flap and corresponding CTG. Power Doppler US was used for assessing blood volume at baseline, 1 week, 1 month, 6 months and 12 months post-surgery for assessing blood-flow dynamics at the implant and palatal donor sites. The speed-weighted and power-weighted colour pixel density (CPPD) were computed from colour velocity (CV) and colour power (CP), respectively.

resultsA mean increase in CV of 199.25% was observed at the midfacial region of the implant sites after 1 week compared to baseline. CV and CP were increased in all sites at 1 week and 1 month. At 6 and 12 months, the mean CV appeared lower than baseline at the implant sites. CCPD was increased at the palatal donor sites and at the great palatine foramen areas at the 1-week and 1-month post-operative evaluations.

conclusionsPower Doppler US is a non-invasive and valuable tool for estimating tissue perfusion and CPPD variation during different phases of intra-oral soft tissue graft healing.

Indexed as

Dental ImplantsConnective TissueGingivoplastyHumansPerfusionPilot ProjectsDental Implantsblood-flow circulationblood-flow velocityblood supplyconnective tissue graftdental implantsoft tissue augmentationultrasonography

Identifiers

PMID33465812
PMCPMC8058327

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.