Evidence map›Paper›PMID 33465604›Full record

ArticleDrug and alcohol dependence2021

Patients at a drug detoxification center share perspectives on how to increase hepatitis C treatment uptake: A qualitative study.

Sabrina A Assoumou, Carlos R Sian, Christina M Gebel, Benjamin P Linas, Jeffrey H Samet, Judith A Bernstein

Abstract read
In one paragraph

Article in Drug and alcohol dependence, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Sabrina A AssoumouSection of Infectious Diseases, Department of Medicine, Boston University School of Medicine, Boston Medical Center, 801 Massachusetts Ave., Crosstown Center, 2(nd) Floor, Boston, MA, USA; Section of Infectious Diseases, Department of Medicine, Boston University School of Medicine, 801 Massachusetts Ave., Crosstown Center, 2nd Floor, Boston, MA, USA. Electronic address: sabrina.assoumou@bmc.org.
Carlos R SianSection of Infectious Diseases, Department of Medicine, Boston University School of Medicine, 801 Massachusetts Ave., Crosstown Center, 2nd Floor, Boston, MA, USA. Electronic address: csian@bu.edu.
Christina M GebelBoston University School of Public Health, Boston, MA, USA. Electronic address: cgebel@bu.edu.
Benjamin P LinasSection of Infectious Diseases, Department of Medicine, Boston University School of Medicine, Boston Medical Center, 801 Massachusetts Ave., Crosstown Center, 2(nd) Floor, Boston, MA, USA; Section of Infectious Diseases, Department of Medicine, Boston University School of Medicine, 801 Massachusetts Ave., Crosstown Center, 2nd Floor, Boston, MA, USA; Boston University School of Public Health, Boston, MA, USA. Electronic address: Benjamin.Linas@bmc.org.
Jeffrey H SametBoston University School of Public Health, Boston, MA, USA; Section of General Internal Medicine, Department of Medicine, Boston University School of Medicine, Boston Medical Center, 801 Massachusetts Avenue, 2nd Floor, Boston, MA, 02118, USA. Electronic address: jsamet@bu.edu.
Judith A BernsteinBoston University School of Public Health, Boston, MA, USA; Boston University School of Public Health, Dept of Community Health Sciences, 801 Massachusetts Ave., Crosstown Center, Boston, MA, 02118, USA. Electronic address: jbernste@bu.edu.

Funding

Utilization of health services after engagement with opioid use disorder (OUD) treatment provider by individuals with and without post-traumatic stress disorderP30DA040500 · NIDA · WEILL MEDICAL COLL OF CORNELL UNIV · PI Bruce R Schackman · 2015 to 2026
$20.7M
Researching Effective Strategies to Prevent Opioid Death (RESPOND)R01DA046527 · NIDA · BOSTON MEDICAL CENTER · PI Benjamin P. Linas · 2018 to 2026
$7.2M
Engaging Young People who Inject Drugs into HCV and HIV Care: Administrative Supplement to Promote Research Continuity and RetentionK23DA044085 · NIDA · BOSTON MEDICAL CENTER · PI ASSOUMOU, SABRINA A · 2018 to 2022
$979k
NIDA NIH HHS K23 DA044085NIDA NIH HHS P30 DA040500NIDA NIH HHS R01 DA046527
6 · The paper itself

Abstract

backgroundThe US opioid crisis is associated with a surge in hepatitis C virus (HCV) infections among persons who inject drugs (PWID), and yet the uptake of HCV curative therapy among PWID is low. PURPOSE: To explore potential solutions to overcome barriers to HCV treatment uptake among individuals at a drug detoxification center.

methodsQualitative study with in-depth interviews and thematic analysis of coded data.

resultsPatients (N = 24) had the following characteristics: mean age 37 years; 67 % White, 13 % Black, 8 % Latinx, 4 % Native Hawaiian/Pacific Islander, 8 % other; 71 % with a history of injecting drugs. Most patients with a positive HCV test had not pursued treatment due to few perceived immediate consequences from a positive test and possible complications arising in a distant poorly imagined future. Active substance use was a major barrier to HCV treatment uptake because of disruptions to routine activities. In addition, re-infection after treatment was perceived as inevitable. Patients had suggestions to improve HCV treatment uptake: high-intensity wraparound care characterized by frequent interactions with supportive services; same-day/walk-in options; low-barrier access to substance use treatment; assistance with navigating the health care system; attention to immediate needs, such as housing; and the opportunity to select an approach that best fits individual circumstances.

conclusionsActive substance use was a major barrier to treatment initiation. To improve uptake, affected individuals recommended that HCV treatment be integrated within substance use treatment programs. Such a model should incorporate patient education within low-barrier, high-intensity wraparound care, tailored to patients' needs and priorities.

Indexed as

AdultAntiviral AgentsDelivery of Health CareDrug UsersFemaleHawaiiHepacivirusHepatitis CHumansMaleMiddle AgedPharmaceutical PreparationsQualitative ResearchSubstance Abuse, IntravenousAntiviral AgentsPharmaceutical PreparationsAccess to careHepatitis CLinkage to careMedications for opioid use disorderPersons who inject drugs

Identifiers

PMID33465604
PMCPMC8064807

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.