Evidence map›Paper›PMID 33465325›Full record

ReviewOpen biology2021

Viral pathogenesis of SARS-CoV-2 infection and male reproductive health.

Shubhadeep Roychoudhury, Anandan Das, Niraj Kumar Jha, Kavindra Kumar Kesari, Shatabhisha Roychoudhury, Saurabh Kumar Jha, Raghavender Kosgi, Arun Paul Choudhury, Norbert Lukac, Nithar Ranjan Madhu and 2 more

Open access · goldAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Open biology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
6.0field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 42 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 8 institutions in 4 countries.

Shubhadeep RoychoudhuryDepartment of Life Science and Bioinformatics, Assam University, Silchar, India.
Anandan DasDepartment of Life Science and Bioinformatics, Assam University, Silchar, India.
Niraj Kumar JhaDepartment of Biotechnology, School of Engineering and Technology (SET), Sharda University, Greater Noida, UP, India.
Kavindra Kumar KesariDepartment of Applied Physics, School of Science, Aalto University, Espoo, Finland.
Shatabhisha RoychoudhuryDepartment of Microbiology, R. G. Kar Medical College and Hospital, Kolkata, India.
Saurabh Kumar JhaDepartment of Biotechnology, School of Engineering and Technology (SET), Sharda University, Greater Noida, UP, India.
Raghavender KosgiDepartment of Urology and Andrology, AIG Hospitals, Gachibowli, Hyderabad, India.
Arun Paul ChoudhuryDepartment of Obstetrics and Gynecology, Silchar Medical College and Hospital, Silchar, India.
Norbert LukacFaculty of Biotechnology and Food Sciences, Slovak University of Agriculture in Nitra, Nitra, Slovak Republic.
Nithar Ranjan MadhuDepartment of Zoology, Acharya Prafulla Chandra College, New Barrackpore, North 24 Parganas, West Bengal, India.
Dhruv KumarAmity Institute of Molecular Medicine and Stem Cell Research, Amity University, Noida, India.
Petr SlamaDepartment of Animal Morphology, Physiology and Genetics, Faculty of AgriSciences, Mendel University in Brno, Brno, Czech Republic.
National Institute Of Technology Silchar · INNoida International University · INAmity University · INEspoo Music Institute · FISlovak University of Agriculture in Nitra · SKUniversity Hospital Brno · CZUniversity of Hyderabad · INWest Bengal State University · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Coronavirus disease 2019 (COVID-19) has emerged as a new public health crisis, threatening almost all aspects of human life. Originating in bats, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is transmitted to humans through unknown intermediate hosts, where it is primarily known to cause pneumonia-like complications in the respiratory system. Organ-to-organ transmission has not been ruled out, thereby raising the possibility of the impact of SARS-CoV-2 infection on multiple organ systems. The male reproductive system has been hypothesized to be a potential target of SARS-CoV-2 infection, which is supported by some preliminary evidence. This may pose a global threat to male fertility potential, as men are more prone to SARS-CoV-2 infection than women, especially those of reproductive age. Preliminary reports have also indicated the possibility of sexual transmission of SARS-CoV-2. It may cause severe complications in infected couples. This review focuses on the pathophysiology of potential SARS-CoV-2 infection in the reproductive organs of males along with their invasion mechanisms. The risks of COVID-19 on male fertility as well as the differences in vulnerability to SARS-CoV-2 infection compared with females have also been highlighted.

Indexed as

Reproductive HealthCOVID-19CytokinesDNA FragmentationHumansLymphocytesMaleOxidative StressSARS-CoV-2SpermatozoaCytokinesACE2COVID-19fertilitymale reproductionSARS-CoV-2 infectiontesticular damage

Identifiers

PMID33465325
PMCPMC7881178
OpenAlexW3122850951

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.