Evidence map›Paper›PMID 33465123›Full record

SynthesisPloS one2021

Effect of high-intensity interval training on metabolic parameters in women with polycystic ovary syndrome: A systematic review and meta-analysis of randomized controlled trials.

Isis Kelly Dos Santos, Fernando Antônio Santana de Souza Nunes, Victor Sabino Queiros, Ricardo Ney Cobucci, Pedro Bruch Dantas, Gustavo Mafaldo Soares, Breno Guilherme de Araújo Tinoco Cabral, Tecia Maria de Oliveira Maranhão, Paulo Moreira Silva Dantas

Open access · goldAbstract readMeta-AnalysisSystematic Review
PubMed Full text at PMC Publisher
In one paragraph

Synthesis in PloS one, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers, 6 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed, 6 pooled it
5.0field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 6 syntheses or guidelines pooled it, 40 citations in OpenAlex.

  1. Pooled it
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  5. Efficacy of physical activity in polycystic ovary syndrome treatment.Current opinion in endocrinology, diabetes, and obesity · 2024
    Pooled it
  6. High-intensity interval training effects in cardiorespiratory fitness of lung cancer survivors: a systematic review and meta-analysis.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2022
    Pooled it
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  19. Polycystic ovary syndrome and abdominal fat: is there a relationship?Revista da Associacao Medica Brasileira (1992) · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Isis Kelly Dos SantosGraduate Program in Health Sciences - Federal University of Rio Grande do Norte, Natal, Brazil.ORCID 0000-0001-7615-416X
Fernando Antônio Santana de Souza NunesGraduate Program in Physical Education - Federal University of Rio Grande do Norte, Natal, Brazil.
Victor Sabino QueirosGraduate Program in Physical Education - Federal University of Rio Grande do Norte, Natal, Brazil.
Ricardo Ney CobucciBiotechnology Graduate Program and Medical School - Potiguar University, Natal, Brazil.ORCID 0000-0002-0184-2061
Pedro Bruch DantasGraduate in Biomedicine - Federal University of Rio Grande do Norte, Natal, Brazil.
Gustavo Mafaldo SoaresDepartment of Toco-Gynecology - Federal University of Rio Grande do Norte, Natal, Brazil.
Breno Guilherme de Araújo Tinoco CabralGraduate Program in Physical Education - Federal University of Rio Grande do Norte, Natal, Brazil.
Tecia Maria de Oliveira MaranhãoDepartment of Toco-Gynecology - Federal University of Rio Grande do Norte, Natal, Brazil.
Paulo Moreira Silva DantasGraduate Program in Health Sciences - Federal University of Rio Grande do Norte, Natal, Brazil.
Universidade Federal do Rio Grande do Norte · BRUniversidade Potiguar · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundOur aim was to assess the effect of high-intensity interval training (HIIT) on metabolic parameters and body composition in women with polycystic ovary syndrome (PCOS). METHODS AND ANALYSIS: A systematic review and meta-analysis of randomized controlled trials was conducted using Embase, MEDLINE (via Ovid), PubMed, Sport Discus, Scopus, Web of Science, Cochrane Library and Google Scholar (advanced feature) up to September 2020. Two authors independently screened citations and determined the risk of bias and quality of evidence using the Grading of Recommendations Assessment, Development and Evaluation (GRADE). Meta-analyses were conducted using random effects model.

resultsSeven trials (n = 423) were included in the systematic review. The studies included HIIT interventions vs. moderate exercise or control groups. Most studies were small (average 32, range 24-110 participants) and of relatively short duration (10-16 weeks). The training intensity was performed between 90% and 95% of the maximum heart rate, three times a week, for at least 10 weeks. Insulin resistance, measured using homeostatic model assessment for insulin resistance (HOMA-IR), and body mass index (BMI) showed a significant decrease (MD -0.57; 95% CI, -0.98 to -0.16, p = 0.01), (MD -1.90, 95% CI -3.37, -0.42, p = 0.01) with moderate and high certainty of evidence, respectively.

conclusionResults support that HIIT alone is effective for reducing HOMA-IR and BMI in women with PCOS. However, evidence is limited to discern the effect of HIIT on other outcomes. Future studies with a longer duration (> 16 weeks), larger sample sizes and other outcomes are needed.

Indexed as

Body Mass IndexHigh-Intensity Interval TrainingBody CompositionFemaleFollicle Stimulating HormoneHumansLipidsLuteinizing HormonePolycystic Ovary SyndromeRandomized Controlled Trials as TopicTestosteroneTreatment OutcomeFollicle Stimulating HormoneLipidsLuteinizing HormoneTestosterone

Identifiers

PMID33465123
PMCPMC7815156
OpenAlexW3121196457

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.