Evidence map›Paper›PMID 33465022›Full record

ArticleThe journal of spinal cord medicine2022

A scoping review on the effect of cannabis on pain intensity in people with spinal cord injury.

Pavithra A Thomas, Gregory T Carter, Charles H Bombardier

Open access · greenAbstract readScoping Review
In one paragraph

Article in The journal of spinal cord medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.6field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 12 citations in OpenAlex.

  1. Article
  2. Observational
  3. Frontiers in pharmacology · 2023
    Review
  4. Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Pavithra A ThomasDepartment of Rehabilitation Medicine, University of Washington, Seattle, Washington, USA.
Gregory T CarterSt Luke's Rehabilitation Institute, Spokane, Washington, USA.
Charles H BombardierDepartment of Rehabilitation Medicine, University of Washington, Seattle, Washington, USA.ORCID 0000-0003-4758-6283
University of Washington · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

contextThis scoping review examines the current research on the effect of cannabis upon pain intensity in spinal cord injury (SCI) pain. Chronic pain is a significant secondary condition following SCI, and traditional treatments (e.g. opioids, NSAIDs) are often criticized for providing inadequate relief. As a result, there is increasing interest in and use of cannabis and cannabinoid-based medications as an alternative means of pain control.

objectiveThe purpose of this review was to examine the scientific evidence on the effect of cannabis/cannabinoids upon pain intensity in SCI by mapping the current literature.

methodsTwo hundred and fifty-two studies were identified by searching electronic databases for articles published through February 2020. In addition, reviewers scanned the reference lists of identified articles and examined clinicaltrials.gov for unpublished data in this area. Title, abstract, and full-text reviews were completed by two independent reviewers. Data extraction was performed by a single reviewer and verified by a second reviewer.

resultsSix articles covering five treatment studies were included. Studies yielded mixed findings likely due to large variability in methodology, including lack of standardized dosing paradigms, modes of use, and duration of trial.

conclusionsThe current quality and level of evidence is insufficient to draw reliable conclusions of the efficacy of cannabis upon SCI-related pain itensity. We identify specific limitations of past studies and present guidelines for future research.

Indexed as

CannabinoidsCannabisChronic PainSpinal Cord InjuriesAnalgesicsAnalgesics, OpioidAnti-Inflammatory Agents, Non-SteroidalHumansPain MeasurementAnalgesicsAnalgesics, OpioidAnti-Inflammatory Agents, Non-SteroidalCannabinoidsCannabisChronic painMedical marijuanaNeuropathic painSpinal cord injury

Identifiers

PMID33465022
PMCPMC9542582
OpenAlexW3121784285

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.