Evidence map›Paper›PMID 33464827›Full record

ArticleACS nano2021

Integration of Multitargeted Polymer-Based Contrast Agents with Photoacoustic Computed Tomography: An Imaging Technique to Visualize Breast Cancer Intratumor Heterogeneity.

Lei Li, Deepanjali Patil, Greg Petruncio, Kathleen K Harnden, Jisha V Somasekharan, Mikell Paige, Lihong V Wang, Carolina Salvador-Morales

Open access · greenAbstract read
In one paragraph

Article in ACS nano, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
2.2field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 34 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Review
  6. Review
  7. Article
  8. Impact of Nanomedicine in Women's Metastatic Breast Cancer.Small (Weinheim an der Bergstrasse, Germany) · 2024
    Review
  9. Review
  10. Review
  11. Review
  12. Review
  13. Review
  14. Article
  15. Review
  16. Multiscale Photoacoustic Tomography of a Genetically Encoded Near-Infrared FRET Biosensor.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2021
    Article
  17. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Lei LiCaltech Optical Imaging Laboratory, Andrew and Peggy Cherng Department of Medical Engineering and Department of Electrical Engineering, California Institute of Technology, Pasadena, California 91125, United States.
Deepanjali PatilDepartment of Chemistry & Biochemistry, George Mason University, 4400 University Drive, Fairfax, Virginia 22030, United States.
Greg PetruncioDepartment of Chemistry & Biochemistry, George Mason University, 4400 University Drive, Fairfax, Virginia 22030, United States.ORCID 0000-0002-2527-1064
Kathleen K HarndenInova Schar Cancer Institute, 8081 Innovation, Park Drive, Fairfax, Virginia 22031, United States.
Jisha V SomasekharanResearch and Post Graduate Department of Chemistry, MES Keveeyam College, Valanchery, Kerala 676552, India.
Mikell PaigeDepartment of Chemistry & Biochemistry, George Mason University, 4400 University Drive, Fairfax, Virginia 22030, United States.
Lihong V WangCaltech Optical Imaging Laboratory, Andrew and Peggy Cherng Department of Medical Engineering and Department of Electrical Engineering, California Institute of Technology, Pasadena, California 91125, United States.
Carolina Salvador-MoralesDepartment of Chemistry & Biochemistry, George Mason University, 4400 University Drive, Fairfax, Virginia 22030, United States.ORCID 0000-0002-2588-6608
George Mason University · USCalifornia Institute of Technology · USVirginia Cancer Institute · US

Funding

PHOTON TUNNELING: SHEDDING NEW LIGHT ON BIOMEDICINEDP1EB016986 · NIBIB · WASHINGTON UNIVERSITY · PI WANG, LIHONG · 2012 to 2016
$3.8M
IN VIVO IMAGING OF SINGLE CIRCULATING CELLSR01CA186567 · NCI · WASHINGTON UNIVERSITY · PI WANG, LIHONG · 2013 to 2017
$3.6M
Deep brain photoacoustic tomography at single-neuron resolution using arrays of photonic emitters and high-frequency ultrasound transducersU01NS099717 · NINDS · CALIFORNIA INSTITUTE OF TECHNOLOGY · PI ROUKES, MICHAEL L, SHEPARD, KENNETH L · 2016 to 2018
$3.0M
FAST HIGH-RESOLUTION DEEP PHOTOACOUSTIC TOMOGRAPHY OF ACTION POTENTIALS IN BRAINSU01NS090579 · NINDS · WASHINGTON UNIVERSITY · PI WANG, LIHONG · 2014 to 2016
$2.7M
WHOLE-BODY SMALL-ANIMAL PHOTOACOUSTIC-ULTRASONIC COMPUTED TOMOGRAPHYR01EB016963 · NIBIB · WASHINGTON UNIVERSITY · PI ANASTASIO, MARK A · 2013 to 2016
$2.4M
Engineering a novel theranostic device for breast cancer treatment based on multiplexing semiconducting patchy polymeric particlesR15CA213093 · NCI · GEORGE MASON UNIVERSITY · PI SALVADOR-MORALES, CAROLINA · 2017 to 2017
$437k
EPA EP-D-17-020NCI NIH HHS R01 CA186567NCI NIH HHS R15 CA213093NIBIB NIH HHS DP1 EB016986NIBIB NIH HHS R01 EB016963NINDS NIH HHS U01 NS090579NINDS NIH HHS U01 NS099717
6 · The paper itself

Abstract

One of the primary challenges in breast cancer diagnosis and treatment is intratumor heterogeneity (ITH),

Indexed as

Breast NeoplasmsPhotoacoustic TechniquesBreastContrast MediaHumansPolymersTomography, X-Ray ComputedContrast MediaPolymersbreast cancerintratumor heterogeneitymultitargetedpatchy particlessingle-impulse panoramic photoacoustic computed tomography

Identifiers

PMID33464827
PMCPMC8106867
OpenAlexW3124564123

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.