ArticleChemistry (Weinheim an der Bergstrasse, Germany)2021
Specific Ion-Protein Interactions Influence Bacterial Ice Nucleation.
Article in Chemistry (Weinheim an der Bergstrasse, Germany), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
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Who cites it
15 citing papers in PubMed, 44 citations in OpenAlex.
- Biochemical characterization of a fungal ice nucleation protein from Podila clonocystis.Scientific reports · 2026Article
- Impact of Perfluorinated Organic Acids on Bacterial Ice Nucleators.The journal of physical chemistry. B · 2026Article
- Polyol-Induced 100-Fold Enhancement of Bacterial Ice Nucleation Efficiency.The journal of physical chemistry. C, Nanomaterials and interfaces · 2024Article
- Hierarchical assembly and environmental enhancement of bacterial ice nucleators.Proceedings of the National Academy of Sciences of the United States of America · 2024Article
- High-speed cryo-microscopy reveals that ice-nucleating proteins ofScience advances · 2024Article
- Ice nucleation proteins self-assemble into large fibres to trigger freezing at near 0 °C.eLife · 2023Article
- Ice nucleation proteins self-assemble into large fibres to trigger freezing at near 0 °C.bioRxiv : the preprint server for biology · 2023Article
- Impact of hierarchical water dipole orderings on the dynamics of aqueous salt solutions.Nature communications · 2023Article
- Lichen species across Alaska produce highly active and stable ice nucleators.Biogeosciences (Online) · 2023Article
- Solvation, Surface Propensity, and Chemical Reactions of Solutes at Atmospheric Liquid-Vapor Interfaces.Accounts of chemical research · 2022Article
- Orcinol and resorcinol induce local ordering of water molecules near the liquid-vapor interface.Environmental science: atmospheres · 2022Article
- Toward Understanding Bacterial Ice Nucleation.The journal of physical chemistry. B · 2022Article
- Structure and Protein-Protein Interactions of Ice Nucleation Proteins Drive Their Activity.Frontiers in microbiology · 2022Article
- Membranes Are Decisive for Maximum Freezing Efficiency of Bacterial Ice Nucleators.The journal of physical chemistry letters · 2021Article
- Specific Ion-Protein Interactions Influence Bacterial Ice Nucleation.Chemistry (Weinheim an der Bergstrasse, Germany) · 2021Article
Corrections and comments
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Authors and funding
11 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Ice nucleation-active bacteria are the most efficient ice nucleators known, enabling the crystallization of water at temperatures close to 0 °C, thereby overcoming the kinetically hindered phase transition process at these conditions. Using highly specialized ice-nucleating proteins (INPs), they can cause frost damage to plants and influence the formation of clouds and precipitation in the atmosphere. In nature, the bacteria are usually found in aqueous environments containing ions. The impact of ions on bacterial ice nucleation efficiency, however, has remained elusive. Here, we demonstrate that ions can profoundly influence the efficiency of bacterial ice nucleators in a manner that follows the Hofmeister series. Weakly hydrated ions inhibit bacterial ice nucleation whereas strongly hydrated ions apparently facilitate ice nucleation. Surface-specific sum-frequency generation spectroscopy and molecular dynamics simulations reveal that the different effects are due to specific interactions of the ions with the INPs on the surface of the bacteria. Our results demonstrate that heterogeneous ice nucleation facilitated by bacteria strongly depends upon the nature of the ions, and specific ion-protein interactions are essential for the complete description of heterogeneous ice nucleation by bacteria.
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