Trial reportAddiction (Abingdon, England)2021
Effects of cannabis use on alcohol consumption in a sample of treatment-engaged heavy drinkers in Colorado.
Trial report in Addiction (Abingdon, England), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
20 citing papers in PubMed, 19 citations in OpenAlex.
- Acute Effects of Cannabis on Alcohol Craving and Consumption: A Randomized Controlled Crossover Trial.The American journal of psychiatry · 2026Trial
- Comparing the Efficacy of Mindfulness-Based Relapse Prevention Versus Relapse Prevention for Alcohol Use Disorder: A Randomized Control Trial.Journal of studies on alcohol and drugs · 2023Trial
- Cannabis craving and cross-substance substitution during cannabis treatment: Initial insights across seven cannabis use disorder clinical trials.Addictive behaviors · 2026Article
- Nonmonotonic Associations Between Cannabis Use Frequency and Alcohol Use in a Statewide Sample of Young Adults From Washington State.American journal of preventive medicine · 2026Article
- Momentary cannabis effects on alcohol use among adults trying to quit or cut back on drinking.Psychology of addictive behaviors : journal of the Society of Psychologists in Addictive Behaviors · 2026Article
- The Cannabinoid System as a Potential Novel Target for Alcohol-Associated Liver Disease: A Propensity-Matched Cohort Study.Liver international : official journal of the International Association for the Study of the Liver · 2025Article
- Article
- Chronic intermittent ethanol produces nociception through endocannabinoid-independent mechanisms in mice.Neuropharmacology · 2025Article
- Kratom use among ethnobotanical tea bar patrons in Colorado: Subjective drug effects, adverse reactions, and perceived benefits of use.Drug and alcohol dependence reports · 2025Article
- Cannabis administration is associated with reduced alcohol consumption: Evidence from a novel laboratory co-administration paradigm.Drug and alcohol dependence · 2025Article
- Substitution and Complementarity in the Consumption of Alcohol, Cannabis, and Opium.Health economics · 2025Article
- Cannabis use and alcohol-related outcomes among sober living house residents with alcohol use disorders.Drug and alcohol dependence reports · 2025Article
- Chronic intermittent ethanol produces nociception through endocannabinoid-independent mechanisms in mice.bioRxiv : the preprint server for biology · 2025Article
- Is there a relationship between abuse of alcohol and illicit drugs seen in hair results?Drug testing and analysis · 2025Article
- Examining substitution behaviors in a non-treatment sample of current drinkers: an exploratory study.Journal of social work practice in the addictions · 2024Article
- The role of sex in daily levels of high-risk alcohol and cannabis co-use.Drug and alcohol dependence reports · 2023Article
- Evaluating substance use outcomes of recreational cannabis legalization using a unique co-twin control design.The American journal of drug and alcohol abuse · 2023Article
- Past-month binge drinking and cannabis use among middle-aged and older adults in the United States, 2015-2019.Alcohol (Fayetteville, N.Y.) · 2023Article
- Patterns of Cannabis and Alcohol Co-Use: Substitution Versus Complementary Effects.Alcohol research : current reviews · 2022Review
- Pharmacological interventions for alcohol use disorder: novel insights from recent clinical trials.Expert review of clinical pharmacologyReview
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 3 institutions in 1 country.
Funding
Abstract
BACKGROUND AND
aimsCannabis is commonly used among people who drink alcohol, but evidence suggests a nuanced relationship between alcohol consumption and cannabis use. In particular, among individuals undergoing alcohol treatment the impact of cannabis on alcohol intake may depend upon cannabis use frequency. We aimed to test the effects of within-day cannabis use on total drinks consumed and likelihood of binge drinking on a given day among all participants and compare these relationships between males and females and between individuals who reported infrequent and frequent cannabis use.
designThis observational study is a substudy of a larger randomized controlled trial (RCT). Individuals were included from the RCT if they reported any cannabis use and were divided into groups based on cannabis use patterns. Alcohol use was compared within and between groups.
settingIndividuals were recruited from 2016 to 2020 from community and university settings in Denver and Boulder, CO, USA.
participantsOf the 182 individuals enrolled in the RCT, 96 cannabis-using subjects were included in these analyses. MEASUREMENTS: Subjects completed a time-line follow-back (TLFB) at baseline, 4, 8 (end of treatment) and 20 weeks. Daily data on alcohol and cannabis use from the TLFB at all time-points were analyzed.
findingsAcross the sample (n = 96), individuals drank approximately 29% fewer drinks [95% confidence interval (CI) = 18-39%, P < 0.001] and were 2.06 times (95% CI =1.37-3.08, P < 0.001) less likely to have a binge-drinking episode on days that cannabis was used compared with days that cannabis was not used. These patterns were observed in males, females and the infrequent and frequent cannabis use groups. Findings were inconclusive regarding differences in the association between cannabis use and alcohol outcomes when comparing males and females and when comparing infrequent and frequent cannabis use groups.
conclusionsHeavy drinkers engaged in treatment to reduce their alcohol consumption who also use cannabis appear to increase their cannabis use on days when they reduce their alcohol consumption.
Indexed as
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.