Evidence map›Paper›PMID 33464539›Full record

ReviewPain and therapy2021

Cervical Proprioception Impairment in Neck Pain-Pathophysiology, Clinical Evaluation, and Management: A Narrative Review.

Baogan Peng, Liang Yang, Yongchao Li, Tanghua Liu, Yanqing Liu

9 registry-linked trialsOpen access · goldAbstract readReview
In one paragraph

Review in Pain and therapy, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 9 registered trials, which are not on this map. Cited by 95 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
95citing papers in PubMed, 2 pooled it
18.1field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05229393 nacompletednot on this mapstarted 2022, after this paper: background citation

The Effectiveness of Manual Therapy to the Cervical Spine and Diaphragm,Combined With Breathing Reeducation Exercises, in Patients With Non-specific Chronic Neck Pain: A Randomized Controlled Trial

TypeinterventionalSponsorUniversity of West AtticaRan2022 to 2023Enrolled90ConditionsChronic Neck PainArmsCervical plus Diaphragmatic Manual Therapy plus Breathing Reeducation Exercises, Cervical Manual Therapy plus sham Diaphragmatic Manual Therapy, Conventional Physiotherapy Program
NCT05750472 completednot on this mapstarted 2023, after this paper: background citation

Neck Awareness, Cognitive Function and Left/Right Judgment Performance in Individuals With Neck Pain: A Cross-sectional Study

TypeobservationalSponsorBahçeşehir UniversityRan2023 to 2023Enrolled70ConditionsNeck Pain
NCT06034223 nacompletednot on this mapstarted 2023, after this paper: background citation

Effect of Proprioceptive Training Using Head Mounted Laser in Chronic Mechanical Neck Pain

TypeinterventionalSponsorShifa Tameer-e-Millat UniversityRan2023 to 2023Enrolled36ConditionsMechanical Neck PainArmsProprioceptive training using head mounted laser, Conventional Physical therpay
NCT06459518 nacompletednot on this mapstarted 2024, after this paper: background citation

Effectiveness of Bowen Technique vs Muscle Energy Technique in Mechanical Neck Pain Among Desktop Users.

TypeinterventionalSponsorRiphah International UniversityRan2024 to 2025Enrolled36ConditionsNeck Pain, Musculoskeletal ManipulationArmsBowen Therapy along with conventional therapy, Muscle Energy Technique with Conventional Therapy
NCT06558318 completednot on this mapstarted 2024, after this paper: background citation

The Role of Temporomandibular Joint Dysfunction on Proprioception, Pain-related Parameters, and Body Awareness

TypeobservationalSponsorNagihan AcetRan2024 to 2025Enrolled60ConditionsTemporomandibular Joint Disorders, Temporomandibular DisorderArmsAssessment of temporomandibular dysfunction
NCT06559397 completednot on this mapstarted 2024, after this paper: background citation

Proprioceptive Puzzle: The Effect of Cervical Proprioceptive Errors on Quantitative Sensory Tests and Body Awareness in Young Adults

TypeobservationalSponsorNagihan AcetRan2024 to 2025Enrolled60ConditionsCervical Proprioceptive Error in Healthy Young IndividualsArmsAssessment of cervical proprioception
NCT06679335 nacompletednot on this mapstarted 2024, after this paper: background citation

Examining the Effect of Lateralization Imagery Training on EEG Brain Oscillations, Pain Intensity, Proprioception, Kinesiophobia and Body Awareness in Individuals With Chronic Neck Pain

TypeinterventionalSponsorBahçeşehir UniversityRan2024 to 2025Enrolled34ConditionsChronic Pain, Neck PainArmsLateralization Imagery Training
NCT06832748 nanot yet recruitingnot on this mapstarted 2025, after this paper: background citation

Feasibility of a Virtual Reality Based Sensorimotor Training Intervention for Patients with Chronic Traumatic Neck Pain

TypeinterventionalSponsorLuleå Tekniska UniversitetRan2025 to 2025Enrolled20ConditionsNeck PainArmsVR neck training, Endurance neck training
NCT07181798 not yet recruitingnot on this mapstarted 2025, after this paper: background citation

Evaluation of Cervical Position and Movement Sense Using Computer Vision Technology in Healthy Individuals

TypeobservationalSponsorNevsehir Haci Bektas Veli UniversityRan2025 to 2026Enrolled74ConditionsCervical Proprioception
3 · Its place in the literature

Who cites it

95 citing papers in PubMed, 2 syntheses or guidelines pooled it, 178 citations in OpenAlex.

  1. Pooled it
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  3. Effects of Dynamic Neck Sensorimotor Biofeedback Training in Individuals With Mechanical Neck Pain: A Pilot Randomized Controlled Trial.Physiotherapy research international : the journal for researchers and clinicians in physical therapy · 2026
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35 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Baogan PengDepartment of Spinal Surgery, The Third Medical Center, General Hospital of the Chinese People's Liberation Army, Beijing, China. pengbaogan@163.com.
Liang YangDepartment of Spinal Surgery, The Third Medical Center, General Hospital of the Chinese People's Liberation Army, Beijing, China.
Yongchao LiDepartment of Spinal Surgery, The Third Medical Center, General Hospital of the Chinese People's Liberation Army, Beijing, China.
Tanghua LiuDepartment of Algology, Lizhuang Tongji Hospital, Yibin, Sichuan, China.
Yanqing LiuDepartment of Algology, Beijing Tiantan Hospital, Capital Medical University, Beijing, China.
Chinese People's Liberation Army · CNCapital Medical University · CNTongji Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Neck pain is very common, but most of the causes are unknown, making diagnosis and treatment extremely challenging. Current studies have found that one of the main problems in patients with neck pain is the impairment of cervical proprioception, which subsequently leads to cervical sensorimotor control disturbances. Cervical spine has a very delicate proprioceptive system that plays a crucial role in controlling posture and balance. Cervical proprioceptive impairment in neck pain occurs through a variety of mechanisms. Experimental neck muscle pain induced by injection of hypertonic saline results in inhibition of the activation of painful muscle; chronic neck pain causes structural and functional impairment of cervical muscles; excessive activation of mechanoreceptors in degenerative cervical discs and facet joints produces a large number of erroneous sensory signals. Clinical examinations to assess the link between structural pathology and neck pain have been unsuccessful, opening the way for the development of function-based tests. To date, eight neck sensorimotor control tests have been reported to evaluate patients with chronic neck pain. Although some tests may involve different subsystems (such as oculomotor system and vestibular system), all tests measure sensorimotor control in the neck, and the most commonly used is cervical joint position error (JPE) test. Current studies support the effectiveness of exercises targeting different aspects of sensorimotor function, in particular retraining aimed at improving cervical proprioception and muscle coordination. Based on the available evidence, it is recommended that patients with neck pain should be assessed and managed for cervical proprioceptive impairment and sensorimotor control disturbances.

Indexed as

Cervical joint position errorCervical proprioceptionCervical proprioceptorCervical sensorimotor controlNeck painPathophysiologyRehabilitation

Identifiers

PMID33464539
PMCPMC8119582
OpenAlexW3125664634

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

and 3 more above

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.