Evidence map›Paper›PMID 33463997›Full record

ArticleKardiologia polska2021

Comparison of left ventricular mechanical dyssynchrony parameters between exercise and adenosine triphosphate stress tests using gated single-photon emission computed tomography myocardial perfusion imaging.

Jianzhou Shi, Yanli Zhou, Priyaranjan Kata, Sheilabi Seeburun, Cheng Wang, Dianfu Li, Zhixin Jiang, Weihua Zhou

Open access · diamondAbstract read
In one paragraph

Article in Kardiologia polska, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact, top 99% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 2 countries.

Jianzhou ShiDepartment of Cardiology, the First Affiliated Hospital of Nanjing Medical University (Jiangsu Province Hospital), Nanjing, China
Yanli ZhouDepartment of Cardiology, the First Affiliated Hospital of Nanjing Medical University (Jiangsu Province Hospital), Nanjing, China
Priyaranjan KataSchool of International Education, Nanjing Medical University, Nanjing, China
Sheilabi SeeburunSchool of International Education, Nanjing Medical University, Nanjing, China
Cheng WangDepartment of Cardiology, the First Affiliated Hospital of Nanjing Medical University (Jiangsu Province Hospital), Nanjing, China
Dianfu LiDepartment of Cardiology, the First Affiliated Hospital of Nanjing Medical University (Jiangsu Province Hospital), Nanjing, China
Zhixin JiangDepartment of Cardiology, the First Affiliated Hospital of Nanjing Medical University (Jiangsu Province Hospital), Nanjing, China
Weihua ZhouCollege of Computing, Michigan Technological University, Houghton, Michigan, United States
Nanjing Medical University · CNJiangsu Province Hospital · CNMichigan Technological University · US

Funding

American Heart Association-American Stroke Association 17AIREA33700016
6 · The paper itself

Abstract

backgroundLeft ventricular mechanical dyssynchrony (LVMD) can be induced after stress test. However, no studies have compared the influence of different stress‑inducing methods on LVMD parameters.

aimsThe aim of the study was to determine whether there is a difference between exercise and adenosine triphosphate (ATP) stress tests in terms of changes in LVMD parameters assessed using gated single‑photon emission computed tomography myocardial perfusion imaging (GSPECT MPI).

methodsA total of190 patients who underwent 99mTc ‑sestamibi GSPECT MPI were consecutively enrolled. Treadmill exercise and ATP stress tests were performed in 95 patients each. Normal myocardial perfusion was defined as the summed stress score (SSS) ≤3 and summed rest score (SRS) ≤3, myocardial ischemia as SSS >3 and SRS ≤3, and myocardial infarction as SSS >3 and SRS >3. Parameters of LVMD, including phase standard deviation (PSD), phase bandwidth (PBW), skewness, and kurtosis were compared. Subtraction was made between values during stress and rest phases to acquire ∆PSD, ∆PBW, ∆skewness, and ∆kurtosis Results: There were no differences in LVMD parameters between the exercise and ATP groups. The same results were obtained in the normal perfusion, ischemia, and infarction subgroups. Furthermore, no differences were observed in ∆PSD (median [interquartile range, IQR], 0.25 [-2.3 to 3.1] vs 0.42 (-1.7 to 3.1]; P = 0.73), ∆PBW (median [IQR], 1 [-7 to 11] vs 1 [-6 to 11]; P = 0.95), ∆skewness (mean [SD], -0.06 [0.63] vs 0 [0.81]; P = 0.53), and ∆kurtosis (median [IQR], -0.47 [-4.2 to 4.3] vs -0.42 [-4.8 to 5.2]; P = 0.73) between the exercise and ATP stress‑inducing methods.

conclusionsThere are no differences between the exercise and ATP stress tests in terms of changes in LVMD parameters. Thus, the 2 methods can be used alternatively.

Indexed as

Myocardial Perfusion ImagingVentricular Dysfunction, LeftAdenosine TriphosphateExercise TestHumansTomography, Emission-Computed, Single-PhotonAdenosine Triphosphate

Identifiers

PMID33463997
PMCPMC10958524
OpenAlexW3125233747

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.