ArticleClinical and translational gastroenterology2020
The Spectrum of Gastrointestinal Symptoms in Patients With Coronavirus Disease-19: Predictors, Relationship With Disease Severity, and Outcome.
Article in Clinical and translational gastroenterology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers, 2 of them syntheses that pooled it.
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Who cites it
31 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Post-infection irritable bowel syndrome following Coronavirus disease-19: A systematic review and meta-analysis.Indian journal of gastroenterology : official journal of the Indian Society of Gastroenterology · 2024Pooled it
- Are gastrointestinal symptoms associated with higher risk of Mortality in COVID-19 patients? A systematic review and meta-analysis.BMC gastroenterology · 2022Pooled it
- Evaluation of clinical and laboratory manifestations related to the gastrointestinal system and prognosis in hospitalized patients with COVID-19: a prospective cohort study.BMC infectious diseases · 2026Article
- Prevalence and risk factors of long COVID-19 persisting for 2 years in Hainan Province: a population-based prospective study.Scientific reports · 2025Article
- Impact of Hepatic Dysfunction on Mortality among Coronavirus Disease 2019 Patients: An Inhospital Observational Study.Annals of African medicine · 2025Article
- Gastrointestinal Manifestation and In-hospital Mortality among End-Stage Renal Disease Patients with COVID-19: A Single-center Retrospective Cohort Study.Acta medica Philippina · 2025Article
- COVID-19 andAntibiotics (Basel, Switzerland) · 2024Article
- Post-infection functional gastrointestinal disorders following coronavirus disease-19: a prospective follow-up cohort study.BMC infectious diseases · 2023Article
- Early symptoms preceding post-infectious irritable bowel syndrome following COVID-19: a retrospective observational study incorporating daily gastrointestinal symptoms.BMC gastroenterology · 2023Observational
- Comparison of Hospitalized COVID-19 Patients in Terms of Disease Course According to the Presence of Gastrointestinal Symptoms Before and After Admission.The Turkish journal of gastroenterology : the official journal of Turkish Society of Gastroenterology · 2023Article
- Serological response to vaccination against coronavirus disease-19 in patients with inflammatory bowel disease.Indian journal of gastroenterology : official journal of the Indian Society of Gastroenterology · 2023Article
- Relationship between anal swab PCR for SARS-CoV-2 with gastrointestinal clinical manifestations and severity of COVID-19 infection in Indonesia.F1000Research · 2023Article
- SARS-CoV-2 and gastrointestinal diseases.Frontiers in microbiology · 2023Review
- Meta-analysis of the demographic and prognostic significance of gastrointestinal symptoms in COVID-19 patients.JGH open : an open access journal of gastroenterology and hepatology · 2022Article
- Clues from the Pandora's Box: Frequency of Acute Abdominal Symptoms in COVID-19 and Its Association with Inflammatory Markers-a Cross-Sectional Study.The Indian journal of surgery · 2022Article
- Twelve Months with COVID-19: What Gastroenterologists Need to Know.Digestive diseases and sciences · 2022Review
- Gastrointestinal perforation and vascular thrombosis in patients with corona virus disease-19: A life-threatening problem.Indian journal of gastroenterology : official journal of the Indian Society of Gastroenterology · 2022Article
- Factors associated with differential COVID-19 mortality rates in the SEAR nations: a narrative review.IJID regions · 2022Review
- Thrombosis leading to acute abdomen in corona virus disease- 19:A case series.Indian journal of gastroenterology : official journal of the Indian Society of Gastroenterology · 2022Article
- Global research production pertaining to gastrointestinal involvement in COVID-19: A bibliometric and visualised study.World journal of gastrointestinal surgery · 2022Article
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Authors and funding
13 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionWe prospectively studied the frequency, spectrum, and predictors of gastrointestinal (GI) symptoms among patients with coronavirus disease-19 (COVID-19) and the relationship between GI symptoms and the severity and outcome.
methodsConsecutive patients with COVID-19, diagnosed in a university hospital referral laboratory in northern India, were evaluated for clinical manifestations including GI symptoms, their predictors, and the relationship between the presence of these symptoms, disease severity, and outcome on univariate and multivariate analyses.
resultsOf 16,317 subjects tested for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) RNA in their oropharyngeal and nasopharyngeal swabs during April-May 2020, 252 (1.5%) were positive. Of them, 208 (82.5%) were asymptomatic; of the 44 symptomatic patients, 18 (40.9%) had non-GI symptoms, 15 (34.1%) had a combination of GI and non-GI symptoms, and 11 (25.0%) had GI symptoms only. Thirty-three had mild-to-moderate disease, 8 severe, and 5 critical. Five patients (1.98%) died. On multivariate analysis, the factors associated with the presence of GI symptoms included the absence of contact history and presence of non-GI symptoms and comorbid illnesses. Patients with GI synptoms more often had severe, critical illness and fatal outcome than those without GI symptoms. DISCUSSION: Eighty-two percent of patients with COVID-19 were asymptomatic, and 10.3% had GI symptoms; severe and fatal disease occurred only in 5% and 2%, respectively. The presence of GI symptoms was associated with a severe illness and fatal outcome on multivariate analysis. Independent predictors of GI symptoms included the absence of contact history, presence of non-GI symptoms, and comorbid illnesses.(Equation is included in full-text article.).
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