Evidence map›Paper›PMID 33463863›Full record

Observational studyAnnals of noninvasive electrocardiology : the official journal of the International Society for Holter and Noninvasive Electrocardiology, Inc2021

Electrocardiographic markers of increased risk of sudden cardiac death in patients with COVID-19 pneumonia.

Mohammed Alareedh, Hussein Nafakhi, Foaad Shaghee, Ahmed Nafakhi

Open access · goldAbstract readObservational Study
In one paragraph

Observational study in Annals of noninvasive electrocardiology : the official journal of the International Society for Holter and Noninvasive Electrocardiology, Inc, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 1 pooled it
2.7field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 1 synthesis or guideline pooled it, 18 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Review
  5. Article
  6. Article
  7. Article
  8. Altered cardiac autonomic function after recovery from COVID-19.Annals of noninvasive electrocardiology : the official journal of the International Society for Holter and Noninvasive Electrocardiology, Inc · 2022
    Article
  9. COVID-19 and Cardiac Arrhythmias: a Contemporary Review.Current treatment options in cardiovascular medicine · 2022
    Review
  10. Article
  11. Article
  12. Response of the authors regarding article "Electrocardiographic markers of increased risk of sudden cardiac death in patients with COVID-19 pneumonia".Annals of noninvasive electrocardiology : the official journal of the International Society for Holter and Noninvasive Electrocardiology, Inc · 2021
    Article
  13. Letter to the Editor regarding article "Electrocardiographic markers of increased risk of sudden cardiac death in patients with COVID-19 pneumonia".Annals of noninvasive electrocardiology : the official journal of the International Society for Holter and Noninvasive Electrocardiology, Inc · 2021
    Article
  14. Electrocardiographic markers of increased risk of sudden cardiac death in patients with COVID-19 pneumonia.Annals of noninvasive electrocardiology : the official journal of the International Society for Holter and Noninvasive Electrocardiology, Inc · 2021
    Observational
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 2 countries.

Mohammed AlareedhInternal Medicine Department, Medicine College, University of Kufa, Najaf, Iraq.
Hussein NafakhiInternal Medicine Department, Medicine College, University of Kufa, Najaf, Iraq.ORCID 0000-0002-0238-0460
Foaad ShagheeInternal Medicine Department, Faculty of Medicine, Jabir Ibn Hayyan Medical University, Kufa, Iraq.
Ahmed NafakhiResearch Unit, Najaf Health Bureau, Ministry of Health, Najaf, Iraq.
University of Kufa · IQMinistry of Health · IQ

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundLittle is known about the role of ECG markers of increased risk of sudden cardiac death during the acute period of coronavirus disease 2019 ( COVID-19) pneumonia.

objectivesTo evaluate ECG markers of sudden cardiac death on admission, including the index of cardiac electrophysiological balance (iCEB) (QTc/QRS) and transmural dispersion of repolarization (TDR) (T from peak to end (Tp-e) interval and Tp-e/QTc), in patients with COVID-19 pneumonia. PATIENTS AND

methodsThis cross-sectional study included 63 patients with newly diagnosed COVID-19 pneumonia who presented to the outpatient clinic or admitted to the respiratory care unit between August 20 and September 15, 2020. Forty-six persons matched for sex and age were selected from data collected before COVID-19 pandemic.

resultsQRS and QTc showed a significant prolongation in patients with COVID-19 pneumonia compared to the controls (87 vs. 78, p < .00, and 429 versus. 400, p < .00, respectively). After categorization of patients with COVID-19 pneumonia into 3 groups according to the severity of pneumonia as mild-moderate, severe, and critical groups, a decreased values of QRS were observed in the critical COVID-19 pneumonia group compared to severe and mild-moderate COVID-19 pneumonia groups (p = .04) while increased values of QTc and iCEB(QTc/QRS) were noted in critical COVID-19 pneumonia group compared to other 2 groups(p < .00).

conclusionsPatients with COVID-19 pneumonia showed significant changes in repolarization and conduction parameters compared to controls. Patients with mild to severe COVID-19 pneumonia may be at low risk for torsades de pointes development.

Indexed as

CausalityComorbidityCOVID-19Cross-Sectional StudiesDeath, Sudden, CardiacElectrocardiographyFemaleHumansIraqMaleMiddle AgedRisk AssessmentSARS-CoV-2COVID-19ECGmarkerspneumoniasudden death

Identifiers

PMID33463863
PMCPMC7995115
OpenAlexW3124200704

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.