ReviewChemistry (Weinheim an der Bergstrasse, Germany)2021
Ladderane Natural Products: From the Ground Up.
Review in Chemistry (Weinheim an der Bergstrasse, Germany), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
What it found
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Who cites it
7 citing papers in PubMed.
- Ladder-shaped molecules for the masses.Nature chemistry · 2026Article
- Concise synthesis and strain-release diversification of bridgehead-substituted [2]-ladderanes.Nature chemistry · 2026Article
- Accessing ladder-shape azetidine-fused indoline pentacycles through intermolecular regiodivergent aza-Paternò-Büchi reactions.Nature communications · 2024Article
- Lewis Acid-Promoted [2 + 2] Cycloadditions of Allenes and Ketenes: Versatile Methods for Natural Product Synthesis.Accounts of chemical research · 2023Article
- Stereoretentive Formation of Cyclobutanes from Pyrrolidines: Lessons Learned from DFT Studies of the Reaction Mechanism.The Journal of organic chemistry · 2023Article
- [2]-Ladderanes as isosteres for meta-substituted aromatic rings and rigidified cyclohexanes.Nature communications · 2022Article
- Stereoselective Synthesis of Cyclobutanes by Contraction of Pyrrolidines.Journal of the American Chemical Society · 2021Article
Corrections and comments
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Authors and funding
2 authors.
Funding
Abstract
The ladderane family of natural products are well known for their linearly concatenated cyclobutane skeletal structure. Owing to their unique carbocyclic framework, several chemical syntheses have been reported since their discovery in 2002. The focus of this review is to showcase the novel tactics that have been used to generate the ladderane core and the challenges that are associated with the synthesis of these unusual and complex natural products.
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Registered trials
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