Evidence map›Paper›PMID 33463773›Full record

ArticleJournal of veterinary internal medicine2020

Effect of prior general anesthesia or sedation and antiseizure drugs on the diagnostic utility of wireless video electroencephalography in dogs.

Thomas Parmentier, Gabrielle Monteith, Miguel A Cortez, Franziska Wielaender, Andrea Fischer, Tarja S Jokinen, Hannes Lohi, Sean Sanders, Veronique Sammut, Tricia Tai and 1 more

Abstract read
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In one paragraph

Article in Journal of veterinary internal medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Thomas ParmentierDepartment of Biomedical Sciences, Ontario Veterinary College, University of Guelph, Guelph, Ontario, Canada.ORCID https://orcid.org/0000-0002-8992-1476
Gabrielle MonteithDepartment of Clinical Studies, Ontario Veterinary College, University of Guelph, Guelph, Ontario, Canada.
Miguel A CortezDivision of Neurology, Department of Paediatrics, Faculty of Medicine, University of Toronto, Peter Gilgan Center Research Learning, SickKids Research Institute, Toronto, Ontario, Canada.
Franziska WielaenderClinic of Small Animal Medicine, Ludwig-Maximilians Universität München, Munich, Germany.ORCID https://orcid.org/0000-0002-3113-5659
Andrea FischerClinic of Small Animal Medicine, Ludwig-Maximilians Universität München, Munich, Germany.ORCID https://orcid.org/0000-0001-7094-1947
Tarja S JokinenDepartment of Equine and Small Animal Medicine, University of Helsinki, Helsinki, Finland.
Hannes LohiDepartment of Veterinary Biosciences and Department of Medical and Clinical Genetics, University of Helsinki and the Folkhälsan Research Center, Helsinki, Finland.
Sean SandersSeattle Veterinary Specialists, Seattle, Washington, USA.
Veronique SammutVCA West LA, Los Angeles, California, USA.
Tricia TaiVCA West LA, Los Angeles, California, USA.
Fiona M K JamesDepartment of Clinical Studies, Ontario Veterinary College, University of Guelph, Guelph, Ontario, Canada.ORCID https://orcid.org/0000-0003-4331-4993

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAmbulatory wireless video electroencephalography (AEEG) is the method of choice to discriminate epileptic seizures from other nonepileptic episodes. However, the influence of prior general anesthesia (GA), sedation, or antiseizure drug (ASD) on the diagnostic ability of AEEG is unknown. HYPOTHESIS/

objectivesThe use of sedation/GA or ASD treatment before AEEG recording may affect the diagnostic ability of AEEG and the time to first abnormality on AEEG. ANIMALS: A total of 108 client-owned dogs undergoing ambulatory AEEG for paroxysmal episodes.

methodsRetrospective cohort study. Proportions of diagnostic AEEG and time to first abnormality were compared between dogs that received sedation/GA or neither for instrumentation as well as dogs receiving at least 1 ASD and untreated dogs.

resultsAmbulatory EEG was diagnostic in 60.2% of all dogs including 49% of the sedation/GA dogs and 68% of dogs that received neither (odds ratio [OR], 2.25; 95% confidence interval [CI], 1.02-5.00; P = .05). The AEEG was diagnostic in 51% of dogs receiving at least 1 ASD and 66% of untreated dogs (OR, 1.95; 95% CI, 0.9-4.3; P = .11). No difference was found in time to first abnormality between sedation/GA or neither or ASD-treated or untreated dogs (P = .1 and P = .3 respectively). Ninety-five percent of dogs had at least 1 abnormality within 277 minutes. CONCLUSION AND CLINICAL IMPORTANCE: Sedation/GA and concurrent ASD administration were not identified as confounding factors for decreasing AEEG diagnostic capability nor did they delay the time to first abnormality. A 4-hour minimal recording period is recommended.

Indexed as

Dog DiseasesPharmaceutical PreparationsAnesthesia, GeneralAnimalsDogsElectroencephalographyRetrospective StudiesSeizuresPharmaceutical PreparationsEEGepilepsymovement disorderparoxysmal episodeveterinary neurology

Identifiers

PMID33463773
PMCPMC7517491

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.