ArticleJournal of veterinary internal medicine2020
Clinicopathologic characteristics, pathology, and prognosis of 77 dogs with focal segmental glomerulosclerosis.
Article in Journal of veterinary internal medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
12 citing papers in PubMed, 12 citations in OpenAlex.
- Survival of dogs with glomerular disease in Europe: insights from the European Veterinary Renal Pathology Service.Journal of veterinary internal medicine · 2026Article
- Clinico-pathological and renal morphological findings in dogs naturally infected with Dirofilaria repens.BMC veterinary research · 2026Article
- A compared histopathological study on kidneys and eye bulbs in distinct clinical presentations of canine leishmaniasis by Leishmania infantum.Veterinary research communications · 2024Article
- Severe glomerular fibrin thrombosis in a dog.The Journal of veterinary medical science · 2024Article
- Urinary Electrophoretograms Performed by Capillary Electrophoresis: Comparison between Dogs and Cats.Gels (Basel, Switzerland) · 2023Article
- Proteinuria and Electrophoretic Pattern in Dogs with Comorbidities Associated with Chronic Kidney Disease.Animals : an open access journal from MDPI · 2023Article
- Effect of hypertension on the long-term prognosis of children with primary focal segmental glomerulosclerosis-a retrospective cohort study.Translational pediatrics · 2023Article
- Glo-In-One: holistic glomerular detection, segmentation, and lesion characterization with large-scale web image mining.Journal of medical imaging (Bellingham, Wash.) · 2022Article
- Treatment of proteinuria in dogs with telmisartan: A retrospective study.Journal of veterinary internal medicine · 2021Article
- Clinicopathologic characteristics, pathology, and prognosis of 77 dogs with focal segmental glomerulosclerosis.Journal of veterinary internal medicine · 2020Article
- Analysis of survival among biopsy-determined categories of kidney disease in dogs.Journal of veterinary internal medicineArticle
- Clinical and Pathologic Characterization of Proteinuric Kidney Disease in Australian and New Zealand Dogs.Journal of veterinary internal medicineArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 1 institution in 1 country.
Funding
Abstract
backgroundFocal segmental glomerulosclerosis (FSGS) is a common cause of nonimmune complex glomerulopathy and the prognosis and clinicopathologic findings associated with this condition have not been described in dogs.
objectiveTo characterize the presentation and identify clinical factors associated with the survival of dogs with FSGS. ANIMALS: Seventy-seven dogs diagnosed with FSGS based on evaluation of renal biopsy samples submitted to the International Veterinary Renal Pathology Service.
methodsRetrospective review of medical records of dogs biopsied for evaluation of proteinuria between January 2015 and May 2017.
resultsThe incidence of FSGS among all dogs biopsied for proteinuria was 26%. Significantly more females (48; 62.3%) than males (29; 37.7%) were affected (P = .04). At the time of biopsy, median serum creatinine concentration (SCr) was 1.2 mg/dL (range, 0.3-8.7), median serum albumin concentration (Alb) was 2.8 g/dL (range, 1.1-4.6), median systolic blood pressure was 153.5 mm Hg (range, 95-260), and median urine protein : creatinine ratio was 5.9 (range, 1.4-22). Median survival time after biopsy was 258 days (range, 26-1003) for dogs that died from all causes (n = 32). Factors that were associated with a shorter survival time included SCr ≥ 2.1 mg/dL (P < .01) and Alb < 2 g/dL (P < .01). CONCLUSIONS AND CLINICAL IMPORTANCE: Most dogs with FSGS were female, and although commonly hypertensive, azotemia, severe hypoalbuminemia and ascites or edema were observed infrequently. Variables significantly associated with survival time were SCr and Alb.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.