Evidence map›Paper›PMID 33463555›Full record

ArticleEndoscopic ultrasound

Urgent and early EUS-guided biliary drainage in patients with acute cholangitis.

Shuntaro Mukai, Takao Itoi, Atsushi Sofuni, Takayoshi Tsuchiya, Kentaro Ishii, Reina Tanaka, Ryosuke Tonozuka, Mitsuyoshi Honjo, Kenjiro Yamamoto, Kazumasa Nagai and 7 more

Open access · greenAbstract read
In one paragraph

Article in Endoscopic ultrasound. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
2.1field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 17 citations in OpenAlex.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors at 1 institution in 1 country.

Shuntaro MukaiDepartment of Gastroenterology and Hepatology, Tokyo Medical University, Tokyo, Japan.
Takao ItoiDepartment of Gastroenterology and Hepatology, Tokyo Medical University, Tokyo, Japan.
Atsushi SofuniDepartment of Gastroenterology and Hepatology, Tokyo Medical University, Tokyo, Japan.
Takayoshi TsuchiyaDepartment of Gastroenterology and Hepatology, Tokyo Medical University, Tokyo, Japan.
Kentaro IshiiDepartment of Gastroenterology and Hepatology, Tokyo Medical University, Tokyo, Japan.
Reina TanakaDepartment of Gastroenterology and Hepatology, Tokyo Medical University, Tokyo, Japan.
Ryosuke TonozukaDepartment of Gastroenterology and Hepatology, Tokyo Medical University, Tokyo, Japan.
Mitsuyoshi HonjoDepartment of Gastroenterology and Hepatology, Tokyo Medical University, Tokyo, Japan.
Kenjiro YamamotoDepartment of Gastroenterology and Hepatology, Tokyo Medical University, Tokyo, Japan.
Kazumasa NagaiDepartment of Gastroenterology and Hepatology, Tokyo Medical University, Tokyo, Japan.
Yukitoshi MatsunamiDepartment of Gastroenterology and Hepatology, Tokyo Medical University, Tokyo, Japan.
Yasutsugu AsaiDepartment of Gastroenterology and Hepatology, Tokyo Medical University, Tokyo, Japan.
Takashi KurosawaDepartment of Gastroenterology and Hepatology, Tokyo Medical University, Tokyo, Japan.
Hiroyuki KojimaDepartment of Gastroenterology and Hepatology, Tokyo Medical University, Tokyo, Japan.
Toshihiro HommaDepartment of Gastroenterology and Hepatology, Tokyo Medical University, Tokyo, Japan.
Hirohito MinamiDepartment of Gastroenterology and Hepatology, Tokyo Medical University, Tokyo, Japan.
Yuichi NagakawaDepartment of Gastrointestinal and Pediatric Surgery, Tokyo Medical University, Tokyo, Japan.
Tokyo Medical University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND AND

objectivesEUS-guided biliary drainage (EUS-BD) has been reported as an effective alternative drainage technique. However, clinical data on EUS-BD for patients with acute cholangitis (AC) are limited. The aim of this study was to analyze the clinical outcomes of EUS-BD in patients with AC. PATIENTS AND

methodsNineteen patients with AC who underwent urgent or early drainage (within 96 h) by EUS-guided hepaticoenterostomy (EUS-HES) between January 2014 and November 2019 were retrospectively reviewed. Furthermore, the clinical outcomes of EUS-HES using a plastic stent in the AC group (n = 15) were compared to those in the non-AC group (n = 88).

resultsIn the 19 AC cases, the technical and clinical success rate was 100% with 5.3% of moderate adverse events (biliary peritonitis [n = 1]). Regarding the comparison between the AC group and the non-AC group, the clinical success rate was 100% in both groups and the adverse event rate was not statistically significantly different (P = 0.88). Although the recurrent biliary obstruction (RBO) rate was not statistically significantly different (P = 0.43), the early RBO rate was statistically significantly higher in the AC group (26.7% vs. 3.4%, P < 0.001). Kaplan-Meier curves showed that AC was associated with a shorter time to RBO (P = 0.046). The presence of AC was found to be an independent risk factor of early RBO (odds ratio = 10.3; P = 0.005).

conclusionsUrgent or early biliary drainage (within 96 h) by EUS-BD can be a feasible and safe alternative procedure for patients with AC, although there is a tendency of early RBO.

Indexed as

acute cholangitisendoscopic biliary drainageEUS-guidedEUS-guided biliary drainagehepaticoenterostomyplastic stent

Identifiers

PMID33463555
PMCPMC8248306
OpenAlexW3119416118

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.