Evidence map›Paper›PMID 33462779›Full record

ArticleCellular and molecular neurobiology2022

Lentiviral Expression of Rabies Virus Glycoprotein in the Rat Hippocampus Strengthens Synaptic Plasticity.

Soheil Ghassemi, Tara Asgari, Hadi Mirzapour-Delavar, Shayan Aliakbari, Hamid Gholami Pourbadie, Christophe Prehaud, Monique Lafon, Alireza Gholami, Kayhan Azadmanesh, Nima Naderi and 1 more

Open access · greenAbstract read
In one paragraph

Article in Cellular and molecular neurobiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.3field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 11 citations in OpenAlex.

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  9. The Effects of the Fraction Isolated from IranianIranian journal of pharmaceutical research : IJPR
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 2 countries.

Soheil GhassemiDepartment of Physiology and Pharmacology, Pasteur Institute of Iran, Tehran, Iran.ORCID http://orcid.org/0000-0001-8652-6190
Tara AsgariDepartment of Physiology and Pharmacology, Pasteur Institute of Iran, Tehran, Iran.ORCID http://orcid.org/0000-0003-1668-6820
Hadi Mirzapour-DelavarDepartment of Physiology and Pharmacology, Pasteur Institute of Iran, Tehran, Iran.ORCID http://orcid.org/0000-0002-1559-7175
Shayan AliakbariDepartment of Physiology and Pharmacology, Pasteur Institute of Iran, Tehran, Iran.ORCID http://orcid.org/0000-0001-5381-9253
Hamid Gholami PourbadieDepartment of Physiology and Pharmacology, Pasteur Institute of Iran, Tehran, Iran. h_gholamipour@pasteur.ac.ir.ORCID http://orcid.org/0000-0002-7634-7428
Christophe PrehaudInstitut Pasteur, Unité de Neuroimmunologie Virale, UMR 3569, CNRS, Paris, France.ORCID http://orcid.org/0000-0001-9183-4649
Monique LafonInstitut Pasteur, Unité de Neuroimmunologie Virale, UMR 3569, CNRS, Paris, France.ORCID http://orcid.org/0000-0002-4423-7996
Alireza GholamiWHO Collaborating Center for Reference and Research on Rabies, Pasteur Institute of Iran, Tehran, Iran.ORCID http://orcid.org/0000-0003-0706-2821
Kayhan AzadmaneshDepartment of Virology, Pasteur Institute of Iran, Tehran, Iran.ORCID http://orcid.org/0000-0002-7165-9043
Nima NaderiDepartment of Pharmacology and Toxicology, School of Pharmacy, Shahid Beheshti University of Medical Sciences, Tehran, Iran.ORCID http://orcid.org/0000-0003-4591-8918
Mohammad SayyahDepartment of Physiology and Pharmacology, Pasteur Institute of Iran, Tehran, Iran. sayyahm2@pasteur.ac.ir.ORCID http://orcid.org/0000-0003-0603-2444
Pasteur Institute of Iran · IRCentre National de la Recherche Scientifique · FRShahid Beheshti University of Medical Sciences · IR

Funding

Pasteur Institute of Iran 868
6 · The paper itself

Abstract

Rabies virus (RABV) is a neurotropic virus exclusively infecting neurons in the central nervous system. RABV encodes five proteins. Among them, the viral glycoprotein (RVG) plays a key role in viral entry into neurons and rabies pathogenesis. It was shown that the nature of the C-terminus of the RABV G protein, which possesses a PDZ-binding motif (PBM), modulates the virulence of the RABV strain. The neuronal protein partners recruited by this PBM may alter host cell function. This study was conducted to investigate the effect of RVG on synaptic function in the hippocampal dentate gyrus (DG) of rat. Two μl (10

Indexed as

Rabies virusAnimalsDentate GyrusElectric StimulationGlycoproteinsHippocampusLong-Term PotentiationNeuronal PlasticityRatsGlycoproteinsDentate gyrusLong-term potentiationPDZ-binding motifPlasticityRabies

Identifiers

PMID33462779
PMCPMC11421698
OpenAlexW3125818727

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.