SynthesisJournal of experimental botany2021
The front line of defence: a meta-analysis of apoplastic proteases in plant immunity.
Synthesis in Journal of experimental botany, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.
What it found
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Who cites it
27 citing papers in PubMed, 45 citations in OpenAlex.
- Apoplast Engineering Unveiled: Multi-Target Strategies to Disarm Pathogens and Elevate Global Food Security.Plant, cell & environment · 2026Review
- Genome-wide identification, characterization and expression analysis of the subtilisin-like protease gene family in Quercus ilex in response to Phytophthora cinnamomi.Scientific reports · 2026Article
- A secreted citrus protease cleaves an outer membrane protein of the Huanglongbing pathogen.Proceedings of the National Academy of Sciences of the United States of America · 2026Article
- Pathogen-inspired engineering of plant protease enhances late blight resistance.Proceedings of the National Academy of Sciences of the United States of America · 2026Article
- Silenced cutters: mechanisms and effects of protease inhibition in plant-pathogen interactions.Journal of experimental botany · 2025Review
- Plant proteases: guardians of proteome integrity and regulators of protein function.Journal of experimental botany · 2025Article
- Lettuce immune responses and apoplastic metabolite profile contribute to reduced internal leaf colonization by human bacterial pathogens.BMC plant biology · 2025Article
- An Activity-Based Proteomics with Two-Dimensional Polyacrylamide Gel Electrophoresis (2D-PAGE) for Identifying Target Proteases inBio-protocol · 2025Article
- Proteasomes accumulate in the plant apoplast where they participate in microbe-associated molecular pattern (MAMP)-triggered pathogen defense.Nature communications · 2025Article
- Bioinspired protocells exhibiting anti-phytopathogenic properties.Frontiers in microbiology · 2025Article
- Learning the language of plant immunity: opportunities and challenges for AI-assisted modelling of fungal effector x host protein complexes.Computational and structural biotechnology journal · 2025Review
- Extracellular plant subtilases dampen cold-shock peptide elicitor levels.Nature plants · 2024Article
- Article
- Pull the fuzes: Processing protein precursors to generate apoplastic danger signals for triggering plant immunity.Plant communications · 2024Review
- Regulation of Proline Accumulation and Protein Secretion in Sorghum under Combined Osmotic and Heat Stress.Plants (Basel, Switzerland) · 2024Article
- Exogenous abscisic acid treatment regulates protein secretion in sorghum cell suspension cultures.Plant signaling & behavior · 2023Article
- The Plant Growth-Promoting Potential of Halotolerant Bacteria Is Not Phylogenetically Determined: Evidence from TwoMicroorganisms · 2023Article
- Planthopper salivary sheath protein LsSP1 contributes to manipulation of rice plant defenses.Nature communications · 2023Article
- Dying in self-defence: a comparative overview of immunogenic cell death signalling in animals and plants.Cell death and differentiation · 2023Review
- The roles of plant proteases and protease inhibitors in drought response: a review.Frontiers in plant science · 2023Review
Corrections and comments
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
Abstract
Secreted proteases act at the front line of defence and play pivotal roles in disease resistance. However, the criteria for apoplastic immune proteases are not always defined and followed. Here, we critically reviewed 46 apoplastic proteases that function in plant defence. We found that most apoplastic immune proteases are induced upon infection, and 17 proteases are genetically required for the immune response. Proteolytic activity has been confirmed for most of the proteases but is rarely shown to be required for biological function, and the apoplastic location of proteases can be subjective and dynamic. Pathogen-derived inhibitors have only been described for cysteine and serine proteases, and the selection pressure acting on immune proteases is rarely investigated. We discuss six different mechanisms by which these proteases mediate plant immunity and summarize the challenges for future research.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.