Evidence map›Paper›PMID 33462339›Full record

ArticleJournal of perinatology : official journal of the California Perinatal Association2021

Association between cerebral oxygen saturation and brain injury in neonates receiving therapeutic hypothermia for neonatal encephalopathy.

Eniko Szakmar, Jennifer Smith, Edward Yang, Joseph J Volpe, Terrie Inder, Mohamed El-Dib

Abstract read
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In one paragraph

Article in Journal of perinatology : official journal of the California Perinatal Association, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
6.0field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 26 citations in OpenAlex.

  1. A narrative review of the clinical applications of renal NIRS and integration with cerebral NIRS in the NICU.Journal of perinatology : official journal of the California Perinatal Association · 2025
    Review
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  12. Comparative evaluation of approach to cardiovascular care in neonatal encephalopathy undergoing therapeutic hypothermia.Journal of perinatology : official journal of the California Perinatal Association · 2022
    Article
  13. Review
  14. Cerebral oxygen saturation-a useful bedside vital sign for neonatal encephalopathy.Journal of perinatology : official journal of the California Perinatal Association · 2021
    Article
  15. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 2 countries.

Eniko SzakmarDepartment of Pediatric Newborn Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.
Jennifer SmithDepartment of Pediatric Newborn Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.
Edward YangDepartment of Radiology, Boston Children's Hospital, Harvard Medical School, Boston, MA, USA.
Joseph J VolpeDepartment of Pediatric Newborn Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.
Terrie InderDepartment of Pediatric Newborn Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.
Mohamed El-DibDepartment of Pediatric Newborn Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA. mel-dib@bwh.harvard.edu.ORCID http://orcid.org/0000-0001-6979-7407
Brigham and Women's Hospital · USBoston Children's Hospital · USSemmelweis University · HU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo assess the association of cerebral oxygen saturation (CrSO STUDY

designThis retrospective cohort study included 49 infants, who received TH for mild to severe neonatal encephalopathy. Of those, 26 presented with brain injury assessed by a novel MRI grading system, whereas 23 had normal MRI scans.

resultsCrSO

conclusionClinically applied NIRS during TH and rewarming can assist in identifying the risk for brain injury.

Indexed as

Brain InjuriesHypothermia, InducedHypoxia-Ischemia, BrainBrainHumansInfantInfant, NewbornOxygenRetrospective StudiesOxygen

Identifiers

PMID33462339
OpenAlexW3122839007

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.