Evidence map›Paper›PMID 33462321›Full record

ArticleScientific reports2021

Deep learning-Based 3D inpainting of brain MR images.

Seung Kwan Kang, Seong A Shin, Seongho Seo, Min Soo Byun, Dong Young Lee, Yu Kyeong Kim, Dong Soo Lee, Jae Sung Lee

Abstract read
In one paragraph

Article in Scientific reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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  10. nnU-Net Deep Learning Method for Segmenting Parenchyma and Determining Liver Volume From Computed Tomography Images.Annals of surgery open : perspectives of surgical history, education, and clinical approaches · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Seung Kwan Kang *Department of Biomedical Sciences, Seoul National University College of Medicine, Seoul, Korea.
Seong A Shin *Department of Biomedical Sciences, Seoul National University College of Medicine, Seoul, Korea.
Seongho SeoDepartment of Electronic Engineering, Pai Chai University, Daejeon, Korea.
Min Soo ByunInstitute of Human Behavioral Medicine, Medical Research Center, Seoul National University, Seoul, Korea.
Dong Young LeeDepartment of Psychiatry, Seoul National University College of Medicine, Seoul, Korea.
Yu Kyeong KimDepartment of Nuclear Medicine, SMG-SNU Boramae Medical Center, Seoul, Korea.
Dong Soo LeeDepartment of Nuclear Medicine, Seoul National University College of Medicine, 103 Daehak-ro, Jongno-gu, Seoul, 03080, Republic of Korea.
Jae Sung LeeDepartment of Biomedical Sciences, Seoul National University College of Medicine, Seoul, Korea. jaes@snu.ac.kr.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The detailed anatomical information of the brain provided by 3D magnetic resonance imaging (MRI) enables various neuroscience research. However, due to the long scan time for 3D MR images, 2D images are mainly obtained in clinical environments. The purpose of this study is to generate 3D images from a sparsely sampled 2D images using an inpainting deep neural network that has a U-net-like structure and DenseNet sub-blocks. To train the network, not only fidelity loss but also perceptual loss based on the VGG network were considered. Various methods were used to assess the overall similarity between the inpainted and original 3D data. In addition, morphological analyzes were performed to investigate whether the inpainted data produced local features similar to the original 3D data. The diagnostic ability using the inpainted data was also evaluated by investigating the pattern of morphological changes in disease groups. Brain anatomy details were efficiently recovered by the proposed neural network. In voxel-based analysis to assess gray matter volume and cortical thickness, differences between the inpainted data and the original 3D data were observed only in small clusters. The proposed method will be useful for utilizing advanced neuroimaging techniques with 2D MRI data.

Indexed as

Deep LearningAgedBrainFemaleHumansImage Processing, Computer-AssistedImaging, Three-DimensionalMagnetic Resonance ImagingMaleNeural Networks, ComputerNeuroimaging

Identifiers

PMID33462321
PMCPMC7814079

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.