Evidence map›Paper›PMID 33462158›Full record

ArticleJournal of neurogastroenterology and motility2021

Esophageal Motility Patterns After Peroral Endoscopic Myotomy in Patients With Achalasia.

Zuzana Vackova, Jan Mares, Jana Krajciova, Zuzana Rabekova, Lucie Zdrhova, Pavla Loudova, Julius Spicak, Petr Stirand, Tomas Hucl, Jan Martinek

Open access · diamondAbstract read
In one paragraph

Article in Journal of neurogastroenterology and motility, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
3.3field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 20 citations in OpenAlex.

  1. Observational
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  3. Article
  4. Review
  5. Article
  6. True peristaltic recovery is uncommon following treatment, particularly endoscopic dilation for achalasia cardia, though pseudo-recovery often occurs.Indian journal of gastroenterology : official journal of the Indian Society of Gastroenterology · 2023
    Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 1 country.

Zuzana VackovaDepartment of Hepatogastroenterology, Institute for Clinical and Experimental Medicine, Prague, Czech Republic.ORCID https://orcid.org/0000-0002-0443-5752
Jan MaresDepartment of Hepatogastroenterology, Institute for Clinical and Experimental Medicine, Prague, Czech Republic.
Jana KrajciovaDepartment of Hepatogastroenterology, Institute for Clinical and Experimental Medicine, Prague, Czech Republic.
Zuzana RabekovaDepartment of Hepatogastroenterology, Institute for Clinical and Experimental Medicine, Prague, Czech Republic.
Lucie ZdrhovaDepartment of Internal Medicine, University Hospital Plzen, Czech Republic.
Pavla LoudovaDepartment of Gastroenterology, Hospital Kolin, Czech Republic; and 5Ostrava University, Faculty of Medicine, Ostrava, Czech Republic.
Julius SpicakDepartment of Hepatogastroenterology, Institute for Clinical and Experimental Medicine, Prague, Czech Republic.
Petr StirandDepartment of Hepatogastroenterology, Institute for Clinical and Experimental Medicine, Prague, Czech Republic.
Tomas HuclDepartment of Hepatogastroenterology, Institute for Clinical and Experimental Medicine, Prague, Czech Republic.
Jan MartinekDepartment of Hepatogastroenterology, Institute for Clinical and Experimental Medicine, Prague, Czech Republic.
Charles University · CZInstitute of Clinical and Experimental Medicine · CZUniversity Hospital Plzen · CZUniversity of Ostrava · CZ

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND/

aimsSeveral studies have reported partial recovery of peristalsis in patients with achalasia after myotomy. The aim of our study is to analyze esophageal motility patterns after peroral endoscopic myotomy (POEM) and to assess the potential predictors and clinical impact of peristaltic recovery.

methodsWe performed a retrospective analysis of prospectively collected data of consecutive patients with achalasia undergoing POEM at a tertiary center. High-resolution manometry (HRM) studies prior to and after POEM were reviewed and the Chicago classification was applied.

resultsA total of 237 patients were analyzed. The initial HRM diagnoses were achalasia type I, 42 (17.7%); type II, 173 (73.0%); and type III, 22 (9.3%). Before POEM, peristaltic fragments were present in 23 (9.7%) patients. After POEM the Chicago classification diagnoses were: 112 absent contractility, 42 type I achalasia, 15 type II, 11 type III, 26 ineffective esophageal motility, 18 esophagogastric junction outflow obstruction, 10 fragmented peristalsis, and 3 distal esophageal spasm. Altogether 68 patients (28.7%) had signs of contractile activity, but the contractions newly appeared in 47 patients (47/214, 22.0%). Type II achalasia showed a trend for appearance of contractions (

conclusionsMore than 20% of achalasia patients have signs of partial recovery of esophageal peristalsis after POEM. It occurs predominantly in type II achalasia but the clinical relevance seems to be negligible.

Indexed as

Esophageal achalasiaManometryMyotomyPeristalsis

Identifiers

PMID33462158
PMCPMC8026367
OpenAlexW3124671301

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.