Evidence map›Paper›PMID 33462075›Full record

ArticleBMJ open diabetes research & care2021

Clinical decision support to improve management of diabetes and dysglycemia in the hospital: a path to optimizing practice and outcomes.

Ariana Pichardo-Lowden, Guillermo Umpierrez, Erik B Lehman, Matthew D Bolton, Christopher J DeFlitch, Vernon M Chinchilli, Paul M Haidet

Open access · goldAbstract read
In one paragraph

Article in BMJ open diabetes research & care, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 1 pooled it
3.1field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 1 synthesis or guideline pooled it, 28 citations in OpenAlex.

  1. American Association of Clinical Endocrinology Clinical Practice Guideline: Developing a Diabetes Mellitus Comprehensive Care Plan-2022 Update.Endocrine practice : official journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists · 2022
    Guideline
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  11. Guardians For Health: A Practical Approach to Improving Quality of Life and Longevity in People with Type 2 Diabetes.Diabetes therapy : research, treatment and education of diabetes and related disorders · 2023
    Review
  12. How Can Point-of-Care Technologies Support In-Hospital Diabetes Care?Journal of diabetes science and technology · 2023
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Ariana Pichardo-LowdenDepartment of Medicine, Penn State Health Milton S Hershey Medical Center, Hershey, Pennsylvania, USA apichardolowden@pennstatehealth.psu.edu.ORCID 0000-0003-4504-4376
Guillermo UmpierrezDepartment of Medicine, Emory University, Atlanta, Georgia, USA.ORCID 0000-0002-3252-5026
Erik B LehmanDepartment of Public Health Sciences, Penn State College of Medicine, Hershey, Pennsylvania, USA.
Matthew D BoltonDepartment of Information Services, Penn State Health Milton S Hershey Medical Center, Hershey, Pennsylvania, USA.
Christopher J DeFlitchDepartment of Emergency Medicine, Penn State Health Milton S Hershey Medical Center, Hershey, Pennsylvania, USA.
Vernon M ChinchilliDepartment of Public Health Sciences, Penn State College of Medicine, Hershey, Pennsylvania, USA.
Paul M HaidetDepartment of Medicine, Public Health Sciences, and Humanities, Penn State Health Milton S Hershey Medical Center, Hershey, Pennsylvania, USA.
Penn State Milton S. Hershey Medical Center · USPennsylvania State University · USEmory University · US

Funding

Applying a System-Based Intervention to Address Barriers in the Management of Dysglycemia and Diabetes in the Hospital Using Electronic Health RecordsK23DK107914 · NIDDK · PENNSYLVANIA STATE UNIV HERSHEY MED CTR · PI PICHARDO-LOWDEN, ARIANA RAQUEL · 2015 to 2019
$815k
NIDDK NIH HHS K23 DK107914
6 · The paper itself

Abstract

introductionInnovative approaches are needed to design robust clinical decision support (CDS) to optimize hospital glycemic management. We piloted an electronic medical record (EMR), evidence-based algorithmic CDS tool in an academic center to alert clinicians in real time about gaps in care related to inpatient glucose control and insulin utilization, and to provide management recommendations. RESEARCH DESIGN AND

methodsThe tool was designed to identify clinical situations in need for action: (1) severe or recurrent hyperglycemia in patients with diabetes: blood glucose (BG) ≥13.88 mmol/L (250 mg/dL) at least once or BG ≥10.0 mmol/L (180 mg/dL) at least twice, respectively; (2) recurrent hyperglycemia in patients with stress hyperglycemia: BG ≥10.0 mmol/L (180 mg/dL) at least twice; (3) impending or established hypoglycemia: BG 3.9-4.4 mmol/L (70-80 mg/dL) or ≤3.9 mmol/L (70 mg/dL); and (4) inappropriate sliding scale insulin (SSI) monotherapy in recurrent hyperglycemia, or anytime in patients with type 1 diabetes. The EMR CDS was active (ON) for 6 months for all adult hospital patients and inactive (OFF) for 6 months. We prospectively identified and compared gaps in care between ON and OFF periods.

resultsWhen active, the hospital CDS tool significantly reduced events of recurrent hyperglycemia in patients with type 1 and type 2 diabetes (3342 vs 3701, OR=0.88, p=0.050) and in patients with stress hyperglycemia (288 vs 506, OR=0.60, p<0.001). Hypoglycemia or impending hypoglycemia (1548 vs 1349, OR=1.15, p=0.050) were unrelated to the CDS tool on subsequent analysis. Inappropriate use of SSI monotherapy in type 1 diabetes (10 vs 22, OR=0.36, p=0.073), inappropriate use of SSI monotherapy in type 2 diabetes (2519 vs 2748, OR=0.97, p=0.632), and in stress hyperglycemia subjects (1617 vs 1488, OR=1.30, p<0.001) were recognized.

conclusionEMR CDS was successful in reducing hyperglycemic events among hospitalized patients with dysglycemia and diabetes, and inappropriate insulin use in patients with type 1 diabetes.

Indexed as

Decision Support Systems, ClinicalDiabetes Mellitus, Type 2HypoglycemiaAdultHospitalsHumansHypoglycemic AgentsHypoglycemic Agentsdecision support techniquesdiabetes mellituselectronic health recordshyperglycemiatype 2

Identifiers

PMID33462075
PMCPMC7816906
OpenAlexW3123092012

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.