Evidence map›Paper›PMID 33462001›Full record

ArticleBMJ case reports2021

Profound diarrhoea and weight loss in an immunocompromised patient.

George Ashton, Alan Shand, Ian Arnott, Shahida Din

Open access · greenAbstract readCase Reports
In one paragraph

Article in BMJ case reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.4field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 8 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

George AshtonGastroenterology Unit, NHS Lothian, Edinburgh, UK george.ashton@nhslothian.scot.nhs.uk.ORCID http://orcid.org/0000-0002-3836-7874
Alan ShandGastroenterology Unit, NHS Lothian, Edinburgh, UK.
Ian ArnottGastroenterology Unit, NHS Lothian, Edinburgh, UK.
Shahida DinGastroenterology Unit, NHS Lothian, Edinburgh, UK.
NHS Lothian · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A 75-year-old man was admitted with a 3-month history of worsening diarrhoea and weight loss. He was on long-term immunosuppression following cardiac transplantation. Investigations revealed herpes simplex oesophagitis and stool samples were positive for norovirus. Treatment with acyclovir and nitazoxanide resulted in a complete resolution of symptoms. Norovirus is a common cause of infectious gastroenteritis, but immunosuppressed patients may present with chronic diarrhoea rather than an acute illness. This case highlights the importance of a low clinical threshold for testing for norovirus infection in immunocompromised patients.

Indexed as

Immunocompromised HostWeight LossAgedCaliciviridae InfectionsChronic DiseaseDiarrheaGastroenteritisHeart TransplantationHumansMaleNorovirusPostoperative Complicationsgastroenterologyinfection (gastroenterology)infectious diseases

Identifiers

PMID33462001
PMCPMC7813290
OpenAlexW3126098766

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.