Evidence map›Paper›PMID 33461732›Full record

ArticleAmerican journal of surgery2021

Does acral lentiginous melanoma subtype account for differences in patterns of care in Black patients?

Taylor M Carter, Paula D Strassle, David W Ollila, Karyn B Stitzenberg, Michael O Meyers, Ugwuji N Maduekwe

Open access · greenAbstract read
In one paragraph

Article in American journal of surgery, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.6field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 13 citations in OpenAlex.

  1. Article
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  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Taylor M CarterDepartment of Surgery, University of North Carolina, Chapel Hill, NC, USA.
Paula D StrassleDepartment of Surgery, University of North Carolina, Chapel Hill, NC, USA.
David W OllilaDivision of Surgical Oncology and Endocrine Surgery, Department of Surgery, University of North Carolina, Chapel Hill, NC, USA.
Karyn B StitzenbergDivision of Surgical Oncology and Endocrine Surgery, Department of Surgery, University of North Carolina, Chapel Hill, NC, USA.
Michael O MeyersDivision of Surgical Oncology and Endocrine Surgery, Department of Surgery, University of North Carolina, Chapel Hill, NC, USA.
Ugwuji N MaduekweDivision of Surgical Oncology and Endocrine Surgery, Department of Surgery, University of North Carolina, Chapel Hill, NC, USA. Electronic address: umaduekwe@med.unc.edu.
University of North Carolina at Chapel Hill · US

Funding

UNC Oncology K12K12CA120780 · NCI · UNIV OF NORTH CAROLINA CHAPEL HILL · PI WILLIAM Y. KIM · 2007 to 2026
$9.6M
In vivo Assessment of Chemotherapy Remodeling of the Bladder Cancer Immune MicroenvironmentR01CA241810 · NCI · UNIV OF NORTH CAROLINA CHAPEL HILL · PI KIM, WILLIAM Y., VINCENT, BENJAMIN G · 2020 to 2024
$2.9M
NCI NIH HHS K12 CA120780NCI NIH HHS R01 CA241810
6 · The paper itself

Abstract

backgroundMelanoma-specific outcomes for Black patients are worse when compared to non-Hispanic white (NHW) patients. We sought to evaluate whether acral lentiginous melanoma, seen more commonly in Black patients, was associated with racial disparities in outcomes

methodsThe National Cancer Database was analyzed for major subtypes of stage I-IV melanoma diagnosed from 2004 to 2016. The association between Black race and (Siegel et al., Jan) 1 acral melanoma diagnosis and (Bradford et al., Apr) 2 receipt of major amputation for surgical management of melanoma was evaluated using multivariable logistic regression.

results251,864 patients were included (1453 Black). Black patients had increased odds of acral melanoma (odds ratio [OR] = 27.6, 95% CI]: 24.4, 31.2) compared to NHW patients. Black patients still had higher odds ratios of major amputation across all stages after adjusting for acral histology and other potential confounders

conclusionsIncreased prevalence of acral melanoma in Black patients does not fully account for increased receipt of major amputation.

Indexed as

Black or African AmericanAgedAmputation, SurgicalCutaneous Malignant MelanomaFemaleHumansLymphatic MetastasisMaleMelanomaMiddle AgedNeoplasm StagingPrognosisSkin NeoplasmsSurvival AnalysisAcral melanomaAmputationMelanomaRace

Identifiers

PMID33461732
PMCPMC8376182
OpenAlexW3114414410

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.