ArticleTrials2021
Managing clinical trials during COVID-19: experience from a clinical research facility.
Article in Trials, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
33 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Monitoring strategies for clinical intervention studies.The Cochrane database of systematic reviews · 2021Pooled it
- Protocol implementation during the COVID-19 pandemic: experiences from a randomized trial of stress ulcer prophylaxis.BMC medical research methodology · 2024Trial
- Trial
- Trial
- Trial
- Trial
- Trial
- Lessons on Resilient Research: Adapting the Tribal Turning Point Study to COVID-19.American Indian and Alaska native mental health research (Online) · 2022Trial
- Factors Associated with Trust and Likelihood of Participation in Pandemic-Related Clinical Trials Among Blacks in the U.S. Deep South.Journal of racial and ethnic health disparities · 2026Article
- PEARLES challenges and solutions to the implementation of clinical research responses to epidemics and pandemics: a scoping review.EClinicalMedicine · 2025Review
- Article
- Academic vs. industry-sponsored trials: A global survey on differences, similarities, and future improvements.Journal of global health · 2024Article
- Serious illness communication skills training for emergency physicians and advanced practice providers: a multi-method assessment of the reach and effectiveness of the intervention.BMC palliative care · 2024Observational
- Resource management and capacity planning for clinical trial sites.Journal of clinical and translational research · 2024Article
- Lessons learned from COVID-19 to overcome challenges in conducting outpatient clinical trials to find safe and effective therapeutics for the next infectious pandemic.Journal of clinical and translational science · 2024Article
- e-Consent in UK academic-led clinical trials: current practice, challenges and the need for more evidence.Trials · 2023Article
- Design of a phase III, double-blind, randomised, placebo-controlled trial of BI 1015550 in patients with idiopathic pulmonary fibrosis (FIBRONEER-IPF).BMJ open respiratory research · 2023Article
- Conducting a phase III clinical trial in children during the COVID- 19 pandemic: Experience and lessons learnt from a clinical research facility of Nepal.Human vaccines & immunotherapeutics · 2023Review
- Crisis of the Clinical Trials Staff Attrition After the COVID-19 Pandemic.JCO oncology practice · 2023Article
- Best Practices from the American Society of Pain and Neuroscience (ASPN) for Clinical Research During a Pandemic or Emergency.Journal of pain research · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
There is a dearth of literature on best practices for managing clinical trials, and little is understood on the role of the clinical trial manager. The COVID-19 pandemic has brought this into focus, and the continuance of clinical trials worldwide has been catapulted into a state of uncertainty as countries enter lockdown to manage the spread of the virus. Participant retention is an ongoing issue in clinical trials, and the concern is that in the current pandemic environment, attrition will be an issue which could potentially jeopardise trial completion. The current situation has necessitated timely problem solving by the trial manager to ensure trials remain open, and most importantly, that participant safety, paramount in clinical trials, is monitored. The purpose of our study is to highlight key issues arising in the management of clinical trials during a pandemic from first-hand experience in a clinical research facility managing both academic and commercial clinical trials. We offer some practical guidance on solution implementation.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.