SynthesisBMC musculoskeletal disorders2021
Distribution and prevalence of musculoskeletal pain co-occurring with persistent low back pain: a systematic review.
Synthesis in BMC musculoskeletal disorders, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
31 citing papers in PubMed, 1 synthesis or guideline pooled it, 62 citations in OpenAlex.
- Prevalence of multimorbid degenerative lumbar spinal stenosis with knee or hip osteoarthritis: a systematic review and meta-analysis.BMC musculoskeletal disorders · 2022Pooled it
- Sex differences in health-related quality of life among individuals at high risk of dementia.European geriatric medicine · 2025Trial
- Multimorbidity and co-occurring musculoskeletal pain do not modify the effect of the SELFBACK app on low back pain-related disability.BMC medicine · 2022Trial
- Trial
- Prevalence and Patterns of Multi-Site Musculoskeletal Disorders Among Occupational Populations in Key Industries - China, 2018-2023.China CDC weekly · 2026Article
- Unique RNA Gene Expression Profile Is Seen in Chronic Non-Specific Low Back Pain.International journal of molecular sciences · 2025Article
- Sex Differences in the Prevalence of Chronic Pain in Mid-Life: A Systematic Review and Meta-Analysis.Biomedicines · 2025Review
- Sex-Related Differences in Chronic Pain: A Narrative Review by a Multidisciplinary Task Force.Medicina (Kaunas, Lithuania) · 2025Review
- Prognostic factors associated with improvement in patients with an episode of non-specific low back pain without radicular syndrome: a prospective observational exploratory study.Chiropractic & manual therapies · 2025Observational
- Association between widespread pain and psychosocial factors in people with knee osteoarthritis: a cross-sectional study of patients from primary care in Denmark.Physiotherapy theory and practice · 2025Article
- Article
- Validation of the Arabic Version of the Fibromyalgia Survey Questionnaire.Journal of pain research · 2025Article
- Changes in Widespread Pain After Surgical Weight Loss in Racialized Adults: A Secondary Analysis From a 2-Year Longitudinal Study.The journal of pain · 2024Article
- Prevalence and risk factors of low back pain in military personnel: a systematic review.EFORT open reviews · 2024Article
- Trends in Physiotherapy of Chronic Low Back Pain Research: Knowledge Synthesis Based on Bibliometric Analysis.Healthcare (Basel, Switzerland) · 2024Review
- Clinical Impact of Thermotherapy and Spinal Twisting Massage on Chronic Non-Specific Spinal Pain.Medicina (Kaunas, Lithuania) · 2024Article
- Change in number of pain sites - which factors are important? A 12-year prospective cohort study.BMC musculoskeletal disorders · 2024Article
- The association between cervical degenerative MRI findings and self-reported neck pain, disability and headache: a cross-sectional exploratory study.Chiropractic & manual therapies · 2023Article
- International Society for the Advancement of Spine Surgery Statement: Restorative Neurostimulation for Chronic Mechanical Low Back Pain Resulting From Neuromuscular Instability.International journal of spine surgery · 2023Article
- Differences in chronic pain prevalence between men and women at mid-life: a systematic review protocol.BMJ open · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 6 institutions in 3 countries.
Funding
Abstract
backgroundCo-occurring musculoskeletal pain is common among people with persistent low back pain (LBP) and associated with more negative consequences than LBP alone. The distribution and prevalence of musculoskeletal pain co-occurring with persistent LBP has not been systematically described, which hence was the aim of this review.
methodsLiterature searches were performed in MEDLINE, Embase, CINAHL and Scopus. We considered observational studies from clinical settings or based on cohorts of the general or working populations involving adults 18 years or older with persistent LBP (≥4 wks) and co-occurring musculoskeletal pain for eligibility. Study selection, data extraction and risk of bias assessment were carried out by independent reviewers. Results are presented according to study population, distribution and location(s) of co-occurring pain.
resultsNineteen studies out of 5744 unique records met the inclusion criteria. Studies were from high-income countries in Europe, USA and Japan. A total of 34,492 people with persistent LBP were included in our evidence synthesis. Methods for assessing and categorizing co-occurring pain varied considerably between studies, but based on the available data from observational studies, we identified three main categories of co-occurring pain - these were axial pain (18 to 58%), extremity pain (6 to 50%), and multi-site musculoskeletal pain (10 to 89%). Persistent LBP with co-occurring pain was reported more often by females than males, and co-occurring pain was reported more often in patients with more disability.
conclusionsPeople with persistent LBP often report co-occurring neck pain, extremity pain or multi-site pain. Assessment of co-occurring pain alongside persistent LBP vary considerable between studies and there is a need for harmonisation of measurement methods to advance our understanding of how pain in different body regions occur alongside persistent LBP. SYSTEMATIC REVIEW REGISTRATION: PROSPERO CRD42017068807 .
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.