Evidence map›Paper›PMID 33461153›Full record

ArticleDrug and alcohol dependence2021

Bidirectional associations between e-cigarette use and alcohol use across adolescence.

Alyssa Lozano, Feifei Liu, Tae Kyoung Lee, Guillermo Prado, Seth J Schwartz, Adam M Leventhal, Annemarie R Kelleghan, Jennifer B Unger, Jessica L Barrington-Trimis

Open access · greenAbstract read
In one paragraph

Article in Drug and alcohol dependence, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
1.9field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 31 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Preventive medicine reports · 2025
    Review
  9. Article
  10. Salivary Metabolic Pathway Alterations in Brazilian E-Cigarette Users.International journal of molecular sciences · 2024
    Article
  11. Predictors of Alcohol Use, Alcohol-Related Problems, and Substance Use Following Adolescent Metabolic and Bariatric Surgery.Annals of surgery open : perspectives of surgical history, education, and clinical approaches · 2024
    Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Review
  18. Review
  19. Article
  20. Addiction-Related Outcomes of Nicotine and Alcohol Co-use: New Insights Following the Rise in Vaping.Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco · 2022
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Alyssa LozanoDepartment of Public Health Sciences, University of Miami Miller School of Medicine, 1120 NW 14th Street, Miami, FL, 33136, USA.
Feifei LiuDepartment of Preventive Medicine, Keck School of Medicine, University of Southern California, 2001 N. Soto Street, Los Angeles, CA, 90089, USA.
Tae Kyoung LeeDepartment of Public Health Sciences, University of Miami Miller School of Medicine, 1120 NW 14th Street, Miami, FL, 33136, USA.
Guillermo PradoSchool of Nursing and Health Studies, University of Miami, Coral Gables, FL, 33143, USA.
Seth J SchwartzDepartment of Public Health Sciences, University of Miami Miller School of Medicine, 1120 NW 14th Street, Miami, FL, 33136, USA; Departments of Kinesiology, Health Education, and Counseling Psychology, College of Education, University of Texas at Austin, 1912 Speedway, Stop D5000, Austin, TX, 78712, USA.
Adam M LeventhalDepartment of Preventive Medicine, Keck School of Medicine, University of Southern California, 2001 N. Soto Street, Los Angeles, CA, 90089, USA.
Annemarie R KelleghanDepartment of Preventive Medicine, Keck School of Medicine, University of Southern California, 2001 N. Soto Street, Los Angeles, CA, 90089, USA; Department of Psychology, University of Southern California, 3620 S. McClintock Ave. SGM 501, Los Angeles, CA, 90089, USA.
Jennifer B UngerDepartment of Preventive Medicine, Keck School of Medicine, University of Southern California, 2001 N. Soto Street, Los Angeles, CA, 90089, USA.
Jessica L Barrington-TrimisDepartment of Preventive Medicine, Keck School of Medicine, University of Southern California, 2001 N. Soto Street, Los Angeles, CA, 90089, USA. Electronic address: jtrimis@usc.edu.
University of Southern California · USUniversity of Miami · US

Funding

USC Tobacco Center of Regulatory ScienceU54CA180905 · NCI · UNIVERSITY OF SOUTHERN CALIFORNIA · PI Adam Matthew Leventhal · 2018 to 2026
$39.0M
Community-Engaged Research on COVID-19 Testing Among Underserved and/or Vulnerable PopulationsU01DA040381 · NIDA · FLORIDA INTERNATIONAL UNIVERSITY · PI BAUM, MARIANNA K · 2015 to 2022
$9.6M
Vaping Nicotine and Cannabis Across Adolescence and Young AdulthoodR01CA229617 · NCI · UNIVERSITY OF SOUTHERN CALIFORNIA · PI BARRINGTON-TRIMIS, JESSICA LOUISE, LEVENTHAL, ADAM MATTHEW · 2019 to 2024
$4.3M
Anhedonia as a Risk Factor and Consequence of Substance UseR01DA033296 · NIDA · UNIVERSITY OF SOUTHERN CALIFORNIA · PI LEVENTHAL, ADAM MATTHEW · 2012 to 2016
$3.4M
Understanding Transitions from Vaping to Smoking Across AdolescenceK01DA042950 · NIDA · UNIVERSITY OF SOUTHERN CALIFORNIA · PI BARRINGTON-TRIMIS, JESSICA LOUISE · 2017 to 2021
$1.0M
NCI NIH HHS R01 CA229617NCI NIH HHS U54 CA180905NIDA NIH HHS K01 DA042950NIDA NIH HHS R01 DA033296NIDA NIH HHS U01 DA040381
6 · The paper itself

Abstract

introductionEvidence on prospective bidirectional associations between e-cigarette and alcohol use among adolescents can inform prevention and policy but is largely absent from the literature.

methodsData were drawn from a prospective cohort of students attending 10 Los Angeles high schools (N = 3396; baseline mean age = 14.1, SD = 0.4). Students completed surveys every 6-months from 2013 to 2017; 8 total waves. Analyses were restricted to (a) individuals who were never users of alcohol (N = 2394) or (b) individuals who were never users of e-cigarettes (N = 2704) at baseline. Repeated-measures, generalized linear mixed models were used to estimate the adjusted odds of past 6-month alcohol and e-cigarette initiation, in separate models.

resultsAmong alcohol never-users at baseline, 15.7 % (N = 375) initiated alcohol use over the study period. Compared to never-users of e-cigarettes, those who reported use of e-cigarettes had 3.5 times the odds of subsequently initiating alcohol use in the following wave (OR = 3.54; 95 % CI: 2.81, 4.47). Stronger associations were observed for males (OR = 4.94; 95 % CI: 3.78, 6.45) than for females (OR = 3.21; 95 % CI: 2.33, 4.41; p

conclusionsE-cigarette and alcohol use can be markers to identify youth at risk for future alcohol and e-cigarette use, respectively. Research examining mechanisms underlying these associations is needed to infer causality.

Indexed as

AdolescentAdolescent BehaviorAlcohol DrinkingCohort StudiesElectronic Nicotine Delivery SystemsFemaleHumansLos AngelesMaleProspective StudiesSchoolsStudentsSurveys and QuestionnairesVapingAdolescenceAlcohole-CigarettesLongitudinal analysisTobacco

Identifiers

PMID33461153
PMCPMC8320369
OpenAlexW3117320318

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.