Evidence map›Paper›PMID 33460557›Full record

ArticleeLife2021

Regulatory roles of

Philip P Adams, Gabriele Baniulyte, Caroline Esnault, Kavya Chegireddy, Navjot Singh, Molly Monge, Ryan K Dale, Gisela Storz, Joseph T Wade

Erratum issuedOpen access · goldAbstract read
In one paragraph

Article in eLife, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 92 papers.

0numbers the graph read from it
0cells of the map it votes in
92citing papers in PubMed
7.5field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

92 citing papers in PubMed, 134 citations in OpenAlex.

  1. Review
  2. Bacterial small regulatory RNAs.Nature reviews. Microbiology · 2026
    Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Review
  10. Article
  11. Article
  12. Article
  13. Origin and adaptive evolutionary trajectory of the 3' UTR-derived sRNA UhpU in Enterobacteriaceae.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Review
  20. Article

32 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 1 country.

Philip P AdamsDivision of Molecular and Cellular Biology, Eunice Kennedy Shriver National Institute of Child Health and Human Development, Bethesda, United States.ORCID 0000-0002-2575-6328
Gabriele BaniulyteWadsworth Center, New York State Department of Health, Albany, United States.ORCID 0000-0003-0235-7938
Caroline EsnaultBioinformatics and Scientific Programming Core, Eunice Kennedy Shriver National Institute of Child Health and Human Development, Bethesda, United States.
Kavya ChegireddyDepartment of Biomedical Sciences, School of Public Health, University at Albany, Albany, United States.
Navjot SinghWadsworth Center, New York State Department of Health, Albany, United States.
Molly MongeWadsworth Center, New York State Department of Health, Albany, United States.
Ryan K DaleBioinformatics and Scientific Programming Core, Eunice Kennedy Shriver National Institute of Child Health and Human Development, Bethesda, United States.
Gisela StorzDivision of Molecular and Cellular Biology, Eunice Kennedy Shriver National Institute of Child Health and Human Development, Bethesda, United States.ORCID 0000-0001-6698-1241
Joseph T WadeWadsworth Center, New York State Department of Health, Albany, United States.ORCID 0000-0002-9779-3160
New York State Department of Health · USEunice Kennedy Shriver National Institute of Child Health and Human Development · USNational Institutes of Health · USUniversity at Albany, State University of New York · US

Funding

NICHD Bioinformatics and Scientific Programming CoreZICHD008986 · NICHD · EUNICE KENNEDY SHRIVER NATIONAL INSTITUTE OF CHILD HEALTH & HUMAN DEVELOPMENT · PI DALE, RYAN · 2019 to 2025
$17.4M
Small Regulatory RNAsZIAHD001608 · NICHD · EUNICE KENNEDY SHRIVER NATIONAL INSTITUTE OF CHILD HEALTH & HUMAN DEVELOPMENT · PI STORZ, GISELA · 2009 to 2025
$16.9M
Pervasive transcription in bacterial genomesDP2OD007188 · OD · WADSWORTH CENTER · PI WADE, JOSEPH THOMAS · 2010 to 2010
$2.4M
RNA-mediated gene regulation in the Lyme disease pathogenZIAHD008995 · NICHD · EUNICE KENNEDY SHRIVER NATIONAL INSTITUTE OF CHILD HEALTH & HUMAN DEVELOPMENT · PI ADAMS, PHILIP · 2021 to 2025
$2.0M
Intramural NIH HHS ZIA HD001608Intramural NIH HHS ZIC HD008986NIH HHS 1Fi2GM133345-01NIH HHS DP2 OD007188
6 · The paper itself

Abstract

Many bacterial genes are regulated by RNA elements in their 5´ untranslated regions (UTRs). However, the full complement of these elements is not known even in the model bacterium

Indexed as

Transcription, Genetic5' Untranslated RegionsEscherichia coliOpen Reading FramesRNA, BacterialRNA, Messenger5' Untranslated RegionsRNA, BacterialRNA, Messengerbase pairing sRNAsE. coliinfectious diseasemicrobiologyRho-dependent terminationRNA-mediated regulationRNA-seqRNA spongesuORF

Identifiers

PMID33460557
PMCPMC7815308
OpenAlexW3123426018

What OpenQuestion holds

Textmetadata
LicenceCC0
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.