ArticlePM & R : the journal of injury, function, and rehabilitation2021
Treatment Recommendations for Phantom Limb Pain in People with Amputations: An Expert Consensus Delphi Study.
Article in PM & R : the journal of injury, function, and rehabilitation, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
33 citing papers in PubMed, 2 syntheses or guidelines pooled it, 62 citations in OpenAlex.
- Beyond traditional therapies: a network meta-analysis on the treatment efficacy for chronic phantom limb pain.Regional anesthesia and pain medicine · 2025Pooled it
- Pooled it
- Trial
- Trial
- Physical and mental health outcomes in Syrian lower limb amputees: the impact of prosthetic rehabilitation in post-conflict settings.BMC musculoskeletal disorders · 2026Observational
- Theoretical foundations of Progressive Motor Training (PMT) for Phantom Limb Pain.Journal of neuroengineering and rehabilitation · 2026Article
- Treatment of residual and phantom limb pain using percutaneous ablation: a systematic review and meta-analysis.Frontiers in rehabilitation sciences · 2026Review
- Myoelectric and Progressive Motor Training for Phantom Limb Pain in People with Amputations During War: A Feasibility Report.Journal of pain research · 2026Article
- War, amputation, and resilience: assessing health-related quality of life in Syrian prosthetic users.International journal for equity in health · 2025Article
- Innovative exploration of phantom limb pain treatment based on extended reality technology.World journal of orthopedics · 2025Review
- Multimodal Approaches for Pain Management and Improving Functional Outcomes Following Amputation.Journal of orthopaedics and sports medicine · 2025Article
- Evaluating Mirror Therapy Protocols in Phantom Limb Pain Clinical Trials: A Scoping Review.Journal of pain research · 2025Review
- Article
- Health-related quality of life among lower limb amputees using prostheses in Nepal: a cross-sectional study.BMC sports science, medicine & rehabilitation · 2024Article
- A Computational Framework for Understanding the Impact of Prior Experiences on Pain Perception and Neuropathic Pain.PLoS computational biology · 2024Article
- Article
- Clinician perspectives on postamputation pain assessment and rehabilitation interventions.Prosthetics and orthotics international · 2024Article
- Immersive VR for upper-extremity rehabilitation in patients with neurological disorders: a scoping review.Journal of neuroengineering and rehabilitation · 2024Article
- Physiotherapy: A potential and novel treatment approach for phantom limb pain in post-amputee patients - A systematic review.British journal of pain · 2024Article
- Virtual embodiment for improving range of motion in patients with movement-related shoulder pain: an experimental study.Journal of orthopaedic surgery and research · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundPhantom limb pain (PLP) is common and often accompanied by serious suffering. Current systematic-review evidence suggests that recommended treatments are no more effective than placebo for reducing PLP. Given the difficulty in conducting a meta-analysis for nonpharmacological treatments and the weak evidence for pharmacological treatments for PLP, consensus on the first-line management of PLP needs to be reached using alternative methods.
objectiveTo reach expert consensus and make recommendations on the effective management of PLP.
designA three-round Delphi design was used.
settingThe study was conducted using e-mail and Google survey tool as the main methods of communication and providing feedback.
participantsThe study included 27 clinicians and researchers from various health disciplines who are experts in PLP management.
methodData were collected using three sequential rounds of anonymous online questionnaires where experts proposed and ranked the treatments for PLP. A consensus was reached on the treatments that were endorsed by 50% or more of the experts.
resultsThirty-seven treatments were proposed for the management of PLP at the beginning of the study. Consensus was reached on seven treatments that were considered effective for managing PLP and on two treatments that were considered ineffective. Graded motor imagery, mirror therapy, amitriptyline, sensory discrimination training, and use of a functional prosthesis were endorsed by most experts because of the available backing scientific evidence and their reported efficacy in clinical practice. Cognitive behavioral therapy and virtual reality training were endorsed by most experts because of their reported efficacy in clinical practice despite indicating a dearth of scientific evidence to support their ranking. Citalopram and dorsal root ganglion pulsed radiofrequency were rejected owing to a lack of relevant scientific evidence.
conclusionThe results of this study suggest that the nonpharmacological treatments endorsed in this study may have an important role in the management of PLP.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.