ReviewPharmacological reports : PR2021
Effects and mechanisms of phthalates' action on neurological processes and neural health: a literature review.
Review in Pharmacological reports : PR, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
34 citing papers in PubMed, 76 citations in OpenAlex.
- Prenatal and childhood exposure to common plasticizers and risk-taking behavior in young adolescents.Environmental research · 2026Article
- Prenatal exposure to di(2-ethylhexyl) phthalate alters the association of glutamatergic proteins with PTEN in the hippocampus of male rat offspring.IBRO neuroscience reports · 2026Article
- Exploratory ATR-FTIR analysis with spectral deconvolution of polymer-like spectral signatures in suspended matter from the Atoyac River, Mexico.Environmental monitoring and assessment · 2026Article
- The Gut-Brain Axis as a Mediator of Environmental Endocrine Disruptors in Attention-Deficit/Hyperactivity Disorder: A Systematic Review and Mechanistic Synthesis.Biological psychiatry global open science · 2026Review
- Effects of Phthalate Exposure on Oral Microbiome Diversity and Enrichment of Gemella and Streptococcus.International dental journal · 2026Article
- Fetal exposure to a mixture of endocrine-disrupting chemicals and biomarkers of male fecundity: A population-based cohort study.Andrology · 2026Article
- Assessment of cat exposure to phthalates through phthalate metabolites analysis in the hair samples.Scientific reports · 2025Article
- A Systematic Review: Migration of Chemical Compounds from Plastic Material Containers in Food and Pharmaceutical Fields.Journal of xenobiotics · 2025Review
- Role of aqueous fenugreek (Trigonella foenum-graecum) extract against DBP-induced renal and adrenal pathologies in male rats.Journal of molecular histology · 2025Article
- Prenatal exposure to phthalates and alternative plasticizers and emotional and behavioral outcomes in early childhood in the Environmental influences on Child Health outcomes (ECHO) cohort.Environment international · 2025Article
- The effects of parental occupational exposures on autism spectrum disorder severity and skills in cognitive and adaptive domains in children with autism spectrum disorder.International journal of hygiene and environmental health · 2025Article
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- Endocrine effect of phthalate metabolites and a butterfly effect of prenatal exposure to androgens on qualitative aspects of female sexual response- an initial survey.International journal of impotence research · 2025Article
- AgNPs/CuNPs/Bragg-PSi substrate subjected to thermal annealing in high-sensitivity detection on crystal violets and diphenyl phthalate.RSC advances · 2025Article
- Disruptive effects of phthalates and their substitutes on adrenal steroidogenesis.Frontiers in endocrinology · 2025Article
- Analysis of Plasticizer Contamination Throughout Olive Oil Production.Molecules (Basel, Switzerland) · 2024Article
- Analytical Investigation of Phthalates and Heavy Metals in Edible Ice from Vending Machines Connected to the Italian Water Supply.Foods (Basel, Switzerland) · 2024Article
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- Early childhood exposure to environmental phenols and parabens, phthalates, organophosphate pesticides, and trace elements in association with attention deficit hyperactivity disorder (ADHD) symptoms in the CHARGE study.Environmental health : a global access science source · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 1 institution in 1 country.
Funding
Abstract
During the period of mass industrial production of plastic products, the quality of human health has decreased significantly, especially in children's neurodevelopmental disorders. Phthalates are endocrine-disrupting chemicals that can induce neurological disorders. This review aims to compile evidence concerning the associations between neurological disorders, such as attention-deficit/hyperactivity disorder, autism spectrum disorder, decreased masculine behavior, and phthalate exposure. Phthalates dysregulate the hypothalamic-pituitary-gonadal, adrenal, and thyroid axis, which is crucial for the neurodevelopmental process. Phthalates interfere with nuclear receptors in various neural structures involved in controlling brain functions and the onset of neurological disorders at the intracellular level. It is critical to increase the current knowledge concerning phthalates' toxicity mechanism to comprehend their harmful effect on human health.
Indexed as
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.