Evidence map›Paper›PMID 33459980›Full record

ArticleMolecular and cellular biochemistry2021

Cytotoxicity of glucoevatromonoside alone and in combination with chemotherapy drugs and their effects on Na

Naira Fernanda Zanchett Schneider, Danusa Menegaz, Andre Luiz Andreotti Dagostin, Lara Persich, Sayonarah C Rocha, Ana Carolina Pacheco Ramos, Vanessa Faria Cortes, Carlos Frederico Leite Fontes, Rodrigo Maia de Pádua, Jennifer Munkert and 5 more

Abstract read
PubMed Publisher
In one paragraph

Article in Molecular and cellular biochemistry, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.6field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Review
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  5. Review
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 6 institutions in 3 countries.

Naira Fernanda Zanchett SchneiderPrograma de Pós-Graduação Em Farmácia, Centro de Ciências da Saúde, Universidade Federal de Santa Catarina, Florianópolis, SC, 88040-900, Brazil.
Danusa MenegazPrograma de Pós-Graduação Em Bioquimica, Núcleo de Bioeletricidade Celular (NUBIOCEL), Centro de Ciências Biologicas, Universidade Federal de Santa Catarina, Florianópolis, SC, Brazil.
Andre Luiz Andreotti DagostinVollum Institute, Oregon Health and Science University, Portland, OR, USA.
Lara PersichPrograma de Pós-Graduação Em Farmácia, Centro de Ciências da Saúde, Universidade Federal de Santa Catarina, Florianópolis, SC, 88040-900, Brazil.
Sayonarah C RochaLaboratório de Bioquímica Celular, Universidade Federal de São João del Rei, Campus Centro-Oeste Dona Lindu, Divinópolis, MG, Brazil.
Ana Carolina Pacheco RamosLaboratório de Bioquímica Celular, Universidade Federal de São João del Rei, Campus Centro-Oeste Dona Lindu, Divinópolis, MG, Brazil.
Vanessa Faria CortesLaboratório de Bioquímica Celular, Universidade Federal de São João del Rei, Campus Centro-Oeste Dona Lindu, Divinópolis, MG, Brazil.
Carlos Frederico Leite FontesLaboratório de Estrutura e Regulação de ATPases, Universidade Federal Do Rio de Janeiro, Rio de Janeiro, Brazil.
Rodrigo Maia de PáduaPrograma de Pós-Graduação Em Ciências Farmacêuticas, Faculdade de Farmácia, Universidade Federal de Minas Gerais, Belo Horizonte, MG, Brazil.
Jennifer MunkertDepartment of Biology, Friedrich-Alexander Universität, Erlangen-Nürnberg, Germany.
Wolfgang KreisDepartment of Biology, Friedrich-Alexander Universität, Erlangen-Nürnberg, Germany.
Fernão Castro BragaPrograma de Pós-Graduação Em Ciências Farmacêuticas, Faculdade de Farmácia, Universidade Federal de Minas Gerais, Belo Horizonte, MG, Brazil.
Leandro A BarbosaLaboratório de Bioquímica Celular, Universidade Federal de São João del Rei, Campus Centro-Oeste Dona Lindu, Divinópolis, MG, Brazil.
Fátima Regina Mena Barreto SilvaPrograma de Pós-Graduação Em Bioquimica, Núcleo de Bioeletricidade Celular (NUBIOCEL), Centro de Ciências Biologicas, Universidade Federal de Santa Catarina, Florianópolis, SC, Brazil.
Cláudia Maria Oliveira SimõesPrograma de Pós-Graduação Em Farmácia, Centro de Ciências da Saúde, Universidade Federal de Santa Catarina, Florianópolis, SC, 88040-900, Brazil. claudia.simoes@ufsc.br.ORCID http://orcid.org/0000-0002-2942-0733
Universidade Federal de Santa Catarina · BRFederal University of São João del-Rei · BRFriedrich-Alexander-Universität Erlangen-Nürnberg · DEUniversidade Federal de Minas Gerais · BROregon Health & Science University · USUniversidade Federal do Rio de Janeiro · BR

Funding

Conselho Nacional de Desenvolvimento Científico e Tecnológico 305878/2016-6Conselho Nacional de Desenvolvimento Científico e Tecnológico 490057/2011-0Conselho Nacional de Desenvolvimento Científico e Tecnológico (BR) 150303/2016-5Coordenação de Aperfeiçoamento de Pessoal de Nível Superior 23080.000686/2017-48Coordenação de Aperfeiçoamento de Pessoal de Nível Superior 400109/2014-0FP7 International Cooperation 295251Ministério da Ciência e Tecnologia 150-2009
6 · The paper itself

Abstract

Cardiac glycosides (CGs) are useful drugs to treat cardiac illnesses and have potent cytotoxic and anticancer effects in cultured cells and animal models. Their receptor is the Na

Indexed as

Carcinoma, Non-Small-Cell LungLung NeoplasmsA549 CellsAntineoplastic Combined Chemotherapy ProtocolsCardenolidesCytotoxinsHumansNeoplasm ProteinsSodium-Potassium-Exchanging ATPaseCardenolidesCytotoxinsglucoevatromonosideNeoplasm ProteinsSodium-Potassium-Exchanging ATPaseCardiac glycosidesGlucoevatromonosideIon channelsLung cancer cellsSynergism

Identifiers

PMID33459980
OpenAlexW3121155599

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.