Evidence map›Paper›PMID 33459932›Full record

ArticlePediatric nephrology (Berlin, Germany)2021

Long-term outcomes during 37 years of pediatric kidney transplantation: a cohort study comparing ethnic groups.

Miriam Davidovits, Lewis Reisman, Roxana Cleper, Nathan Bar-Nathan, Irit Krause, Amit Dagan, Neomi Zanhendler, Gabriel Chodick, Osnat Hocherman, Maya Mor and 2 more

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In one paragraph

Article in Pediatric nephrology (Berlin, Germany), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.6field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 9 citations in OpenAlex.

  1. Linear growth in pediatric kidney transplant recipients.Pediatric nephrology (Berlin, Germany) · 2026
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 3 institutions in 1 country.

Miriam DavidovitsInstitute of Nephrology, Schneider Children's Medical Center of Israel, 49202, Petah Tikva, Israel. doctors@012.net.il.
Lewis ReismanInstitute of Nephrology, Schneider Children's Medical Center of Israel, 49202, Petah Tikva, Israel.
Roxana CleperSackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel.
Nathan Bar-NathanDepartment of Transplantation, Rabin Medical Center, Beilinson Hospital, Petah Tikva, Israel.
Irit KrauseInstitute of Nephrology, Schneider Children's Medical Center of Israel, 49202, Petah Tikva, Israel.
Amit DaganInstitute of Nephrology, Schneider Children's Medical Center of Israel, 49202, Petah Tikva, Israel.
Neomi ZanhendlerInstitute of Nephrology, Schneider Children's Medical Center of Israel, 49202, Petah Tikva, Israel.
Gabriel ChodickSackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel.
Osnat HochermanInstitute of Nephrology, Schneider Children's Medical Center of Israel, 49202, Petah Tikva, Israel.
Maya MorDepartment of Transplantation, Rabin Medical Center, Beilinson Hospital, Petah Tikva, Israel.
Sigal AisnerDepartment of Transplantation, Rabin Medical Center, Beilinson Hospital, Petah Tikva, Israel.
Eytan MorSackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel.
Schneider Children's Medical Center · ILRabin Medical Center · ILTel Aviv University · IL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThis study aimed to evaluate short- and long-term outcomes of kidney transplantation over 37 years in a national referral center and compare outcomes between Israeli Jewish and Arab children.

methodsData on 599 pediatric transplantations performed in 545 children during 1981-2017, including demographic parameters, kidney failure disease profile, and pre-transplant dialysis duration, were retrieved from our computerized database and patient files. Patient and graft survival were estimated using the Kaplan-Meier method.

resultsTwenty-year patient survival was 91.4% for live donor (LD) and 80.2% for deceased donor (DD) kidney recipients. Respective 10-year and 20-year graft survival rates for first kidney-only transplants were 75.2% and 47.0% for LD and 60.7% and 38.4% for DD grafts. Long-term graft survival improved significantly (p < 0.001) over the study period for recipients of both LD and DD allografts and reached 7-year graft survival of 92.0% and 71.3%, respectively. The proportion of DD transplantations was higher in the Arab subpopulation: 73.8% vs. 48.4% (p < 0.001). Graft survival was not associated with age at transplantation and did not differ between the Arab (N = 202) and Jewish children (N = 343). Median (IQR) waiting time on dialysis did not differ significantly between the Arab and Jewish children: 18 (10-30) and 15 (9-30) months, respectively (p Mann-Whitney = 0.312).

conclusionsGood and progressively improving long-term results were obtained in pediatric kidney transplantation at our national referral center, apparently due to expertise gained over time and advances in immunosuppression. Equal access to DD kidney transplant and similar graft survival were found between ethnic groups.

Indexed as

Kidney DiseasesKidney Failure, ChronicKidney TransplantationChildCohort StudiesEthnicityGraft RejectionGraft SurvivalHumansLiving DonorsRenal DialysisTreatment OutcomeEthnic disparitiesGraft survivalKidney transplantPatient survivalPediatric

Identifiers

PMID33459932
OpenAlexW3123119865

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.