Evidence map›Paper›PMID 33459841›Full record

ArticleAbdominal radiology (New York)2021

Ultrasound features help identify patients who can undergo noninvasive management for suspected retained products of conception: a single institutional experience.

Shrilakshmi Vyas, Hailey H Choi, Sara Whetstone, Priyanka Jha, Liina Poder, Dorothy J Shum

Registry-linked trialOpen access · hybridAbstract read
In one paragraph

Article in Abdominal radiology (New York), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07206342 (Evaluation of the Non-inferiority of Resorbable Gelatin Embolization Compared to Embolization Combined With Endometrial Aspiration for the Management of Hemorrhagic Uterine Vascular Abnormalities Following Premature Termination of Pregnancy), which is not on this map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
6.7field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07206342 nanot yet recruitingnot on this mapstarted 2026, after this paper: background citation

Evaluation of the Non-inferiority of Resorbable Gelatin Embolization Compared to Embolization Combined With Endometrial Aspiration for the Management of Hemorrhagic Uterine Vascular Abnormalities Following Premature Termination of Pregnancy

TypeinterventionalSponsorUniversity Hospital, GrenobleRan2026 to 2028Enrolled110ConditionsHemorrhage, Obstetric, Uterine Abnormality, Uterine Artery Embolization, Vaginal Bleeding During PregnancyArmsembolization therapy, embolization followed by aspiration
3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 25 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Article
  6. Review
  7. Retained Products of Conception (RPOC): Diagnosis, Complication & Management.Journal of obstetrics and gynaecology of India · 2023
    Review
  8. Review
  9. Article
  10. Article
  11. Article
  12. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Shrilakshmi VyasDept of Radiology and Biomedical Imaging, University of California San Francisco, 505 Parnassus Avenue, Floor 02, Room 255, Box 0628, San Francisco, CA, 94117, USA.
Hailey H ChoiDept of Radiology and Biomedical Imaging, University of California San Francisco, 505 Parnassus Avenue, Floor 02, Room 255, Box 0628, San Francisco, CA, 94117, USA. Hailey.choi@ucsf.edu.ORCID http://orcid.org/0000-0002-7597-9191
Sara WhetstoneDept of Obstetrics and Gynecology, University of California San Francisco, 505 Parnassus Avenue, San Francisco, CA, 94117, USA.
Priyanka JhaDept of Radiology and Biomedical Imaging, University of California San Francisco, 505 Parnassus Avenue, Floor 02, Room 255, Box 0628, San Francisco, CA, 94117, USA.
Liina PoderDept of Radiology and Biomedical Imaging, University of California San Francisco, 505 Parnassus Avenue, Floor 02, Room 255, Box 0628, San Francisco, CA, 94117, USA.
Dorothy J ShumDept of Radiology and Biomedical Imaging, University of California San Francisco, 505 Parnassus Avenue, Floor 02, Room 255, Box 0628, San Francisco, CA, 94117, USA.
University of California, San Francisco · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesTo evaluate ultrasound (US) features associated with successful noninvasive management for suspected retained products of conception (RPOC).

methodsIn this IRB-approved retrospective study, the radiology report database was queried for pelvic US with keywords of postpartum hemorrhage (PPH) and/or RPOC over a 2-year period. Follow-up exams, US exams without clinical follow-up, suboptimal image quality, and > 1 year from delivery or pregnancy termination were excluded. Charts were reviewed for clinical presentation and management. Two radiologists reviewed images for endometrial thickness, endometrial echogenicity, endometrial vascularity, and enhanced myometrial vascularity (EMV), as well as inner myometrial peak systolic velocity (PSV) and resistive index (RI) where available. Features were assessed for associations with management approach, and test characteristics were calculated.

resultsInitial query yielded 196 exams, and 48 were excluded. A total of 148 patients were included. Mean age was 34.2 years (21-47), and mean time from delivery or pregnancy termination was 40.4 days (0-223). 81 (55%) underwent noninvasive management: 72 (48%) expectant and 9 (6%) medical. 67 (45%) underwent invasive management: 60 (41%) surgical and 7 (5%) uterine artery embolization. There was substantial inter-reader agreement for assessment of EMV (K = 0.78) and endometrial vascularity (K = 0.72). Thin endometrial stripe, avascular endometrium, and absence of EMV were associated with successful noninvasive management (p < 0.05). Thin endometrium (< 10 mm) had specificity (90%), PPV (88%), and likelihood ratio (5.91) in predicting successful noninvasive management.

conclusionEndometrial thickness < 10 mm, avascular endometrium, and absence of EMV are the sonographic features associated with successful noninvasive management for PPH or suspected RPOC.

Indexed as

EndometriumMyometriumAdultFemaleHumansPregnancyRetrospective StudiesUltrasonographyEnhanced myometrial vascularityPelvic ultrasoundPostpartum hemorrhageRetained products of conceptionUterine arteriovenous malformation

Identifiers

PMID33459841
PMCPMC8206055
OpenAlexW3125735113

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.