Evidence map›Paper›PMID 33459726›Full record

ReviewArchivos de cardiologia de Mexico2021

Guidelines for prophylaxis and anti-thrombotic treatment for patients with COVID-19. Consensus of the Latin American Cooperative Group on Hemostasis and Thrombosis (CLAHT)

Cecilia Guillermo-Esposito, Patricia Casais, Gabriela Cesarman-Maus, Fernanda Andrade-Orsi, Rosario Martínez-Rovira, Joao C de-Campos-Guerra, Suely M Rezende, Raúl Izaguirre-Ávila, Raúl Altman, José Ceresetto and 27 more

Open access · diamondAbstract readReview
In one paragraph

Review in Archivos de cardiologia de Mexico, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.1field-weighted citation impact, top 47% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

37 authors at 8 institutions in 4 countries.

Cecilia Guillermo-EspositoCátedra de Hematología, Facultad de Medicina, Hospital de Clínicas, Universidad de la República, Montevideo, Uruguay.
Patricia CasaisDepartamento de Epidemiología Clínica y Evidencia, Instituto de Investigaciones en Salud Pública, Universidad de Buenos Aires, Argentina.
Gabriela Cesarman-MausDepartamento de Hematología, Instituto Nacional de Cancerología, Ciudad de México, México.
Fernanda Andrade-OrsiDepartamento de Patología Clínica, Escuela de Ciencias Médicas, Universidad de Campinas, Campinas-Sao Paulo, Brasil.
Rosario Martínez-RoviraUnidad de Hemostasis y Trombosis, Hospital de Clínicas, Universidad de la República, Montevideo, Uruguay.
Joao C de-Campos-GuerraHospital Israelita Albert Einstein, Centro de Hematología de Sao Paulo, Sao Paulo, Brasil.
Suely M RezendeFacultad de Medicina, Universidad Federal de Minas Gerais, Belo Horizonte, Minas Gerais, Brasil.
Raúl Izaguirre-ÁvilaDepartamento de Hematología, Instituto Nacional de Cardiología Ignacio Chávez, Ciudad de México, México.
Raúl AltmanArgentina
José CeresettoArgentina
Cecilia ColorioArgentina
Cristina DuboscqArgentina
Claudio Martín RosaArgentina
Soledad MolnarArgentina
Diana GarcíaArgentina
Mario Luis TejarinaBolivia
Nelson Nina GarcíaBolivia
Juan Choque PachecoBolivia
Chiara Chindamo J. MaríaBrasil
Gloria Ramos RamosColombia
Guillermo León BasantesColombia
Aura Milena ReynaColombia
Miriam Cantero GuevaraColombia
Mateo Porres AguilarMéxico
Luis MeillónMéxico
Flavio Adrián GrimaldoMéxico
Ludwing Alexander Bacon FonsecaNicaragua
Al Ávila MilordPanamá
Ricardo AguilarPanamá
Rafael AparicioPanamá
Paula de GuggiariParaguay
Gloria ChumpitazPerú
Pedro Pablo GarcíaPerú
Blanca SteffanoUruguay
Sandra DamianoUruguay
Juan SerranoVenezuela
Marisol ZavahraVenezuela
Hospital de Clínicas · UYHospital Israelita Albert Einstein · BRInstituto Nacional de Cancerología · MXInstituto Nacional de Cardiología · MXUniversidad de la República · UYUniversidade Estadual de Campinas (UNICAMP) · BRUniversidade Federal de Minas Gerais · BRUniversity of Buenos Aires · AR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Coagulopathy and thrombosis associated with coronavirus disease 2019 (COVID-19) represent a major issue in the management of this disease. In the past months, clinical studies have demonstrated that COVID-19 patients present with a particular hypercoagulable state, in which a markedly increased D-dimer concomitant with increased levels of fibrinogen are observed. This hypercoagulable state leads to an increased risk of thrombosis, which seems to be higher among those patients with critical symptoms of COVID-19. The best therapeutic approach to prevent thrombotic events in COVID-19 has not been determined yet and several questions regarding thromboprophylaxis therapy, such as the time to initiate anticoagulation, type of anticoagulant and dose regimen, have emerged among physicians. To address these concerns, several medical societies have published position papers to provide the opinion of thrombosis experts on the management of coagulopathy and thrombosis associated with COVID-19. In line with this, the Latin America Cooperative Group of Hemostasis and Thrombosis (Grupo CLAHT) has constituted a panel of experts in thrombosis and hemostasis to discuss the available data on this topic. The aim of this review is to summarize the current evidence regarding hemostatic impairment and thrombotic risk in COVID-19 and to provide a carefully revised opinion of Latin American experts on the thromboprophylaxis and management of thrombotic events and coagulopathy in patients with suspected COVID-19.

Indexed as

COVID-19ThrombosisVenous ThromboembolismAnticoagulantsConsensusHemostasisHumansLatin AmericaAnticoagulantsCOVID-19NeumoníaSARS-CoV-2TromboemboliaTromboprofilaxiaTrombosis

Identifiers

PMID33459726
PMCPMC10161848
OpenAlexW3100669795

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.