Evidence map›Paper›PMID 33459594›Full record

ArticleeLife2021

Ablation of STAT3 in Purkinje cells reorganizes cerebellar synaptic plasticity in long-term fear memory network.

Jeong-Kyu Han, Sun-Ho Kwon, Yong Gyu Kim, Jaeyong Choi, Jong-Il Kim, Yong-Seok Lee, Sang-Kyu Ye, Sang Jeong Kim

Open access · goldAbstract read
In one paragraph

Article in eLife, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
2.2field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 29 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Review
  7. Review
  8. Article
  9. Article
  10. Cerebellum and Emotion Memory.Advances in experimental medicine and biology · 2022
    Article
  11. Article
  12. Cerebellar Circuits for Classical Fear Conditioning.Frontiers in cellular neuroscience · 2022
    Review
  13. Article
  14. Article
  15. Article
  16. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Jeong-Kyu Han *Department of Physiology, Seoul National University College of Medicine, Seoul, Republic of Korea.
Sun-Ho Kwon *Memory Network Medical Research Center, Seoul National University College of Medicine, Seoul, Republic of Korea.
Yong Gyu KimDepartment of Physiology, Seoul National University College of Medicine, Seoul, Republic of Korea.ORCID 0000-0002-4378-6248
Jaeyong ChoiDepartment of Biomedical Sciences, Seoul National University College of Medicine, Seoul, Republic of Korea.
Jong-Il KimDepartment of Biomedical Sciences, Seoul National University College of Medicine, Seoul, Republic of Korea.ORCID 0000-0002-7240-3744
Yong-Seok LeeDepartment of Physiology, Seoul National University College of Medicine, Seoul, Republic of Korea.ORCID 0000-0002-6217-9574
Sang-Kyu YeDepartment of Physiology, Seoul National University College of Medicine, Seoul, Republic of Korea.
Sang Jeong KimDepartment of Brain and Cognitive Sciences, Seoul National University Graduate School, Seoul, Republic of Korea.ORCID 0000-0001-8931-3713
Seoul National University · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Emotional memory processing engages a large neuronal network of brain regions including the cerebellum. However, the molecular and cellular mechanisms of the cerebellar cortex modulating the fear memory network are unclear. Here, we illustrate that synaptic signaling in cerebellar Purkinje cells (PCs)

Indexed as

FearMemory, Long-TermAnimalsMaleMiceNeuronal PlasticityPurkinje CellsSTAT3 Transcription FactorStat3 protein, mouseSTAT3 Transcription FactorAMPA receptorsfear memory networkmouseneurosciencePurkinje cellsSTAT3

Identifiers

PMID33459594
PMCPMC7813544
OpenAlexW3122065523

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.