Evidence map›Paper›PMID 33459462›Full record

ArticleAngewandte Chemie (International ed. in English)2021

Stiffness Tomography of Ultra-Soft Nanogels by Atomic Force Microscopy.

M Friederike Schulte, Steffen Bochenek, Monia Brugnoni, Andrea Scotti, Ahmed Mourran, Walter Richtering

Open access · hybridAbstract read
In one paragraph

Article in Angewandte Chemie (International ed. in English), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
3.0field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 64 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Soft and Deformable Thermoresponsive Hollow Rod-Shaped Microgels.Small (Weinheim an der Bergstrasse, Germany) · 2025
    Article
  5. Capillary-driven self-assembly of soft ellipsoidal microgels at the air-water interface.Proceedings of the National Academy of Sciences of the United States of America · 2024
    Article
  6. Article
  7. Article
  8. Exploring the 3D Conformation of Hard-Core Soft-Shell Particles Adsorbed at a Fluid Interface.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2023
    Article
  9. Article
  10. Article
  11. Article
  12. Review
  13. Stiffness Tomography of Ultra-Soft Nanogels by Atomic Force Microscopy.Angewandte Chemie (International ed. in English) · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

M Friederike SchulteInstitute of Physical Chemistry, RWTH Aachen University, Landoltweg 2, 52056, Aachen, Germany.ORCID http://orcid.org/0000-0002-9411-242X
Steffen BochenekInstitute of Physical Chemistry, RWTH Aachen University, Landoltweg 2, 52056, Aachen, Germany.ORCID http://orcid.org/0000-0001-5841-2815
Monia BrugnoniInstitute of Physical Chemistry, RWTH Aachen University, Landoltweg 2, 52056, Aachen, Germany.ORCID http://orcid.org/0000-0003-2220-3645
Andrea ScottiInstitute of Physical Chemistry, RWTH Aachen University, Landoltweg 2, 52056, Aachen, Germany.ORCID http://orcid.org/0000-0002-8988-330X
Ahmed MourranDWI-Leibniz Institute for Interactive Materials, Forckenbeckstr. 50, 52056, Aachen, Germany.ORCID http://orcid.org/0000-0003-1607-5739
Walter RichteringInstitute of Physical Chemistry, RWTH Aachen University, Landoltweg 2, 52056, Aachen, Germany.ORCID http://orcid.org/0000-0003-4592-8171
RWTH Aachen University · DEDWI – Leibniz Institute for Interactive Materials · DE

Funding

Deutsche Forschungsgemeinschaft (DFG) Sonderforschungsbereich SFB 985 "Functional Microgels and Microgel Systems"
6 · The paper itself

Abstract

The softness of nanohydrogels results in unique properties and recently attracted tremendous interest due to the multi-functionalization of interfaces. Herein, we study extremely soft temperature-sensitive ultra-low cross-linked (ULC) nanogels adsorbed to the solid/water interface by atomic force microscopy (AFM). The ultra-soft nanogels seem to disappear in classical imaging modes since a sharp tip fully penetrates these porous networks with very low forces in the range of steric interactions (ca. 100 pN). However, the detailed evaluation of Force Volume mode measurements allows us to resolve their overall shape and at the same time their internal structure in all three dimensions. The nanogels exhibit an extraordinary disk-like and entirely homogeneous but extremely soft structure-even softer than polymer brushes. Moreover, the temperature-sensitive nanogels can be switched on demand between the ultra-soft and a very stiff state.

Indexed as

atomic force microscopysoft matterstiffness tomographysurface analysistemperature-sensitive nanogels

Identifiers

PMID33459462
PMCPMC7898630
OpenAlexW3093131461

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.