ArticleThe EMBO journal2021
m
Open access · bronzeAbstract read
In one paragraph
Article in The EMBO journal, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers.
0numbers the graph read from it
0cells of the map it votes in
39citing papers in PubMed
3.5field-weighted citation impact, top 6% of its field
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
39 citing papers in PubMed, 52 citations in OpenAlex.
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- Protein arginine methyltransferases in cancer: mechanisms, functions, and therapeutic opportunities.Journal of biomedical science · 2026Review
- RNA modification-mediated multidimensional crosstalk: a novel perspective on gene expression regulation.Genome biology · 2026Review
- Arginine methylation-dependent METTL14-SMN interaction regulates RNA mEMBO reports · 2025Article
- Endothelial Arginine Metabolism in Angiogenesis: Mechanistic Insights from Tissue Repair to Tumor Progression.Metabolites · 2025Review
- Targeting RNA adenosine editing and modification enzymes for RNA therapeutics.Molecular therapy : the journal of the American Society of Gene Therapy · 2025Review
- PRMT1 oligomerization regulates RNA-binding protein cascade to promote pancreatic cancer.Life science alliance · 2025Article
- The importance of physiological and disease contexts in capturing mRNA modifications.Nature structural & molecular biology · 2025Review
- Cardiomyocyte-specific long noncoding RNA Trdn-as induces mitochondrial calcium overload by promoting the mFrontiers of medicine · 2025Article
- Specific sDMA modifications on the RGG/RG motif of METTL14 regulate its function in AML.Cell communication and signaling : CCS · 2025Article
- PRMT1-mediated methylation regulates MLL2 stability and gene expression.Nucleic acids research · 2025Article
- Unveiling the dynamics and therapeutic potential of mInternational journal of biological sciences · 2025Review
- Spliceosomal vulnerability of MYCN-amplified neuroblastoma is contingent on PRMT5-mediated regulation of epitranscriptomic and metabolomic pathways.Cancer letters · 2024Article
- Post-Translational Modifications of RNA-Modifying Proteins in Cellular Dynamics and Disease Progression.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2024Review
- The regulatory role of mGenes & diseases · 2024Review
- Regulations of mFrontiers of medicine · 2024Review
- NAging and disease · 2024Review
- Targeting key RNA methylation enzymes to improve the outcome of colorectal cancer chemotherapy (Review).International journal of oncology · 2024Review
- The competitive landscape of the dsRNA world.Molecular cell · 2024Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
12 authors at 3 institutions in 1 country.
Zhihao WangDepartment of Cancer Genetics and Epigenetics, Beckman Research Institute of City of Hope, Duarte, CA, USA.ORCID 0000-0003-1561-4040
Zhicheng PanBioinformatics Interdepartmental Graduate Program, University of California, Los Angeles, Los Angeles, CA, USA.
Samir AdhikariDepartment of Pathology and Laboratory Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.
Bryan T HaradaDepartments of Chemistry, Biochemistry and Molecular Biology, Institute for Biophysical Dynamics, The University of Chicago, Chicago, IL, USA.ORCID 0000-0002-9683-782X
Lei ShenDepartment of Cancer Genetics and Epigenetics, Beckman Research Institute of City of Hope, Duarte, CA, USA.
Wei YuanDepartment of Cancer Genetics and Epigenetics, Beckman Research Institute of City of Hope, Duarte, CA, USA.
Tharindumala AbeywardanaDepartment of Cancer Genetics and Epigenetics, Beckman Research Institute of City of Hope, Duarte, CA, USA.
Qais Al-HadidDepartment of Cancer Genetics and Epigenetics, Beckman Research Institute of City of Hope, Duarte, CA, USA.
Jeremy M StarkDepartment of Cancer Genetics and Epigenetics, Beckman Research Institute of City of Hope, Duarte, CA, USA.
Chuan HeDepartments of Chemistry, Biochemistry and Molecular Biology, Institute for Biophysical Dynamics, The University of Chicago, Chicago, IL, USA.ORCID 0000-0003-4319-7424
Lan LinDepartment of Pathology and Laboratory Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.ORCID 0000-0002-9905-8928
Yanzhong YangDepartment of Cancer Genetics and Epigenetics, Beckman Research Institute of City of Hope, Duarte, CA, USA.ORCID 0000-0002-1937-4526
City of Hope · USChildren's Hospital of Philadelphia · USHoward Hughes Medical Institute · US
Funding
Transcriptome-wide base-resolution sequencing of pseudouridine in human normal and AD brain tissues-CEGS Admin supplement 2020-2021RM1HG008935 · NHGRI · UNIVERSITY OF CHICAGO · PI HE, CHUAN · 2016 to 2025
$24.4MRegulation of N6-methyladenosine (m6A) deposition by arginine methylationR01GM133850 · NIGMS · BECKMAN RESEARCH INSTITUTE/CITY OF HOPE · PI YANG, YANZHONG · 2019 to 2023
$2.1MRegulation and Function of RNA Editing in Human TranscriptomesR01GM121827 · NIGMS · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI LIN, LAN · 2017 to 2021
$1.9MThe role of mRNA methylation in the progression of endometrial cancerF32CA221007 · NCI · UNIVERSITY OF CHICAGO · PI HARADA, BRYAN TSUTOMU · 2017 to 2019
$179kHoward Hughes Medical InstituteNCI NIH HHS F32 CA221007NHGRI NIH HHS RM1 HG008935NIGMS NIH HHS R01 GM121827NIGMS NIH HHS R01 GM133850
Abstract
The N6-methyladenosine (m
Indexed as
Protein Processing, Post-TranslationalAdenosineAnimalsArginineCytoplasmMethyltransferasesMiceMouse Embryonic Stem CellsProtein-Arginine N-MethyltransferasesRNA Polymerase IITranscriptomeAdenosineArginineMethyltransferasesMettl14 protein, mouseN-methyladenosinePrmt1 protein, mouseProtein-Arginine N-MethyltransferasesRNA Polymerase IIarginine methylationDNA repairPRMT1RGG motifRNA m6A methylation
Identifiers
What OpenQuestion holds
Textmetadata
Read underepoch 390
Registered trials
None linked
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.