Evidence map›Paper›PMID 33459182›Full record

ArticleJournal of biomolecular structure & dynamics2022

Identification of 1,2,3-triazole-phthalimide derivatives as potential drugs against COVID-19: a virtual screening, docking and molecular dynamic study.

Vanderlan Nogueira Holanda, Elton Marlon de Araújo Lima, Welson Vicente da Silva, Rafael Trindade Maia, Rafael de Lima Medeiros, Arabinda Ghosh, Vera Lúcia de Menezes Lima, Regina Celia Bressan Queiroz de Figueiredo

Open access · greenAbstract read
In one paragraph

Article in Journal of biomolecular structure & dynamics, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.6field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 30 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 5 institutions in 3 countries.

Vanderlan Nogueira HolandaLaboratório de Lipídios e Aplicação de Biomoléculas em Doenças Prevalentes e Negligenciadas, Departamento de Bioquímica, Centro de Biociências, Universidade Federal de Pernambuco, Recife, Pernambuco, Brazil.ORCID 0000-0001-5309-0036
Elton Marlon de Araújo LimaLaboratório de Biologia Celular de Patógenos, Instituto Aggeu Magalhães, Departamento de Microbiologia, Instituto Aggeu Magalhães - IAM/FIOCRUZ-PE, Recife, Pernambuco, Brazil.ORCID 0000-0003-0545-2447
Welson Vicente da SilvaLaboratório de Biologia Celular de Patógenos, Instituto Aggeu Magalhães, Departamento de Microbiologia, Instituto Aggeu Magalhães - IAM/FIOCRUZ-PE, Recife, Pernambuco, Brazil.ORCID 0000-0001-5676-6863
Rafael Trindade MaiaCentro de Desenvolvimento Sustentável do Semiárido, Universidade Federal de Campina Grande, Sumé, Paraíba, Brazil.ORCID 0000-0002-5870-1091
Rafael de Lima MedeirosInstituto de Física, Universidade Federal de Alagoas, Maceió, Alagoas, Brazil.ORCID 0000-0003-2360-3595
Arabinda GhoshMicrobiology Division, Department of Botany, Gauhati University, Guwahati, Assam, India.ORCID 0000-0002-3891-5949
Vera Lúcia de Menezes LimaLaboratório de Lipídios e Aplicação de Biomoléculas em Doenças Prevalentes e Negligenciadas, Departamento de Bioquímica, Centro de Biociências, Universidade Federal de Pernambuco, Recife, Pernambuco, Brazil.ORCID 0000-0003-2581-9218
Regina Celia Bressan Queiroz de FigueiredoLaboratório de Biologia Celular de Patógenos, Instituto Aggeu Magalhães, Departamento de Microbiologia, Instituto Aggeu Magalhães - IAM/FIOCRUZ-PE, Recife, Pernambuco, Brazil.ORCID 0000-0001-5806-0944
Universidade Federal de Pernambuco · BRHospital de Magalhães Lemos · PTGauhati University · INUniversidade Federal de Alagoas · BRUniversidade Federal de Campina Grande · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In this work we aimed to perform an

Indexed as

COVID-19 Drug TreatmentHumansMolecular Docking SimulationMolecular Dynamics SimulationPhthalimidesProtease InhibitorsSARS-CoV-2TriazolesPhthalimidesProtease InhibitorsTriazoles123-triazoleAntiviralMD simulationphthalimideSARS-CoV-2

Identifiers

PMID33459182
PMCPMC7832388
OpenAlexW3123880265

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.