Evidence map›Paper›PMID 33459130›Full record

ArticleAutophagy2021

ATG7 is dispensable for LC3-PE conjugation in thioglycolate-elicited mouse peritoneal macrophages.

Nemanja Vujić, Ivan Bradić, Madeleine Goeritzer, Katharina B Kuentzel, Silvia Rainer, Dagmar Kratky, Branislav Radović

Open access · hybridAbstract read
In one paragraph

Article in Autophagy, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
2.7field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 31 citations in OpenAlex.

  1. Article
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  8. Dual role of autophagy in bone metastasis: mechanistic insights and therapeutic targeting.American journal of clinical and experimental urology · 2025
    Review
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  17. Autophagy in gastrointestinal cancers.Frontiers in oncology · 2022
    Review
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  19. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Nemanja VujićGottfried Schatz Research Center, Medical University of Graz, Graz, Austria.ORCID 0000-0003-2977-7799
Ivan BradićGottfried Schatz Research Center, Medical University of Graz, Graz, Austria.
Madeleine GoeritzerGottfried Schatz Research Center, Medical University of Graz, Graz, Austria.
Katharina B KuentzelGottfried Schatz Research Center, Medical University of Graz, Graz, Austria.
Silvia RainerGottfried Schatz Research Center, Medical University of Graz, Graz, Austria.
Dagmar KratkyGottfried Schatz Research Center, Medical University of Graz, Graz, Austria.
Branislav RadovićGottfried Schatz Research Center, Medical University of Graz, Graz, Austria.
Medical University of Graz · AT

Funding

Austrian Science Fund FWF DOC 31Austrian Science Fund FWF P 30882Austrian Science Fund FWF P 32400
6 · The paper itself

Abstract

Thioglycolate-elicited macrophages exhibit abundant conjugation of LC3 with PE (LC3-II). Among other autophagy-related (ATG) proteins, it is proposed that, like in yeast, both ATG5 and ATG7 are essential for LC3 conjugation. Using

Indexed as

AnimalsAutophagyAutophagy-Related Protein 5Autophagy-Related Protein 7Lipid MetabolismMacrolidesMacrophagesMacrophages, PeritonealMiceMice, KnockoutMicrotubule-Associated ProteinsPhosphatidylethanolaminesThioglycolatesAtg5 protein, mouseAtg7 protein, mouseAutophagy-Related Protein 5Autophagy-Related Protein 7bafilomycin A1MacrolidesMap1lc3b protein, mouseMicrotubule-Associated ProteinsphosphatidylethanolaminePhosphatidylethanolaminesThioglycolatesATG3ATG5ATG7LC3-IILC3 lipidationmacrophages

Identifiers

PMID33459130
PMCPMC8632316
OpenAlexW3122109049

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.