Evidence map›Paper›PMID 33458859›Full record

ArticleMagnetic resonance in medicine2021

Measuring

Madhwesha R Rao, Graham Norquay, Neil J Stewart, Jim M Wild

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Magnetic resonance in medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.7field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 13 citations in OpenAlex.

  1. UltrasensitiveAdvanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025
    Review
  2. Review
  3. Blood-brain barrier dysfunction in intensive care unit.Journal of intensive medicine · 2023
    Review
  4. Article
  5. HyperpolarizedMagnetic resonance in medicine · 2022
    Review
  6. Article
  7. MeasuringMagnetic resonance in medicine · 2021
    Article
  8. In vivo methods and applications of xenon-129 magnetic resonance.Progress in nuclear magnetic resonance spectroscopy · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Madhwesha R RaoPOLARIS, Department of Infection, Immunity and Cardiovascular Disease and Insigneo Institute of In-silico Medicine, University of Sheffield, Sheffield, UK.ORCID 0000-0002-4109-4176
Graham NorquayPOLARIS, Department of Infection, Immunity and Cardiovascular Disease and Insigneo Institute of In-silico Medicine, University of Sheffield, Sheffield, UK.ORCID 0000-0002-4108-9035
Neil J StewartPOLARIS, Department of Infection, Immunity and Cardiovascular Disease and Insigneo Institute of In-silico Medicine, University of Sheffield, Sheffield, UK.ORCID 0000-0001-8358-394X
Jim M WildPOLARIS, Department of Infection, Immunity and Cardiovascular Disease and Insigneo Institute of In-silico Medicine, University of Sheffield, Sheffield, UK.ORCID 0000-0002-7246-8660
Insigneo · GB

Funding

Medical Research Council MR/M008894/1
6 · The paper itself

Abstract

purposeThis study develops a tracer kinetic model of xenon uptake in the human brain to determine the transfer rate of inhaled hyperpolarized THEORY AND

methodsTime-resolved MR spectra of hyperpolarized

resultsFor all the acquired NMR spectra, the developed tracer kinetic model fitted the data with tracer transfer coefficients between 0.1 and 0.14.

conclusionIn this study, a tracer kinetic model was developed and validated that estimates the transfer rate of HP

Indexed as

Blood-Brain BarrierXenon IsotopesHumansLungMagnetic Resonance ImagingMagnetic Resonance SpectroscopyXenonXenonXenon Isotopesblood-brain barriergas-exchangehyperpolarized xenon-129time-resolved magnetic resonance spectroscopytracer kinetic model

Identifiers

PMID33458859
PMCPMC7986241
OpenAlexW3122304689

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.