Evidence map›Paper›PMID 33458742›Full record

ReviewCardiovascular research2021

Cardiac troponin and defining myocardial infarction.

Thomas E Kaier, Bashir Alaour, Michael Marber

Abstract readReview
In one paragraph

Review in Cardiovascular research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Article
  5. Review
  6. Review
  7. Article
  8. Review
  9. Observational
  10. Review
  11. Article
  12. Review
  13. Cardiovascular Biomarkers: Tools for Precision Diagnosis and Prognosis.International journal of molecular sciences · 2025
    Review
  14. Article
  15. Article
  16. Cardioprotective effects ofFrontiers in pharmacology · 2025
    Article
  17. Article
  18. Cardiovascular biomarkers: exploring troponin and BNP applications in conditions related to carbon monoxide exposure.The Egyptian heart journal : (EHJ) : official bulletin of the Egyptian Society of Cardiology · 2024
    Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Thomas E KaierKing's College London BHF Centre, The Rayne Institute, 4th Floor, Lambeth Wing, St Thomas' Hospital, Westminster Bridge Road, London SE1 7EH, UK.ORCID 0000-0002-4669-2095
Bashir AlaourKing's College London BHF Centre, The Rayne Institute, 4th Floor, Lambeth Wing, St Thomas' Hospital, Westminster Bridge Road, London SE1 7EH, UK.ORCID 0000-0001-5604-1096
Michael MarberKing's College London BHF Centre, The Rayne Institute, 4th Floor, Lambeth Wing, St Thomas' Hospital, Westminster Bridge Road, London SE1 7EH, UK.ORCID 0000-0002-3463-7128

Funding

British Heart Foundation FS/15/13/31320British Heart Foundation FS/18/78/33902British Heart Foundation TG/15/1/31518Guy's & St Thomas' National Health Service Foundation TrustGuy's and St Thomas' Charity R060701Medical Research Council G1000737Medical Research Council (London, UK) G1000737National Institute for Health Research clinical lectureship CL-2019-17-006UK Department of Health through the National Institute for Health Research Biomedical Research Centre
6 · The paper itself

Abstract

The 4th Universal Definition of Myocardial Infarction has stimulated considerable debate since its publication in 2018. The intention was to define the types of myocardial injury through the lens of their underpinning pathophysiology. In this review, we discuss how the 4th Universal Definition of Myocardial Infarction defines infarction and injury and the necessary pragmatic adjustments that appear in clinical guidelines to maximize triage of real-world patients.

Indexed as

Terminology as TopicBiomarkersConsensusDecision Support TechniquesHumansMyocardial InfarctionPractice Guidelines as TopicPredictive Value of TestsPrognosisTroponinBiomarkersTroponinMyocardial infarctionMyocardial injuryTroponin

Identifiers

PMID33458742
PMCPMC8404461

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.