ArticleMedical image computing and computer-assisted intervention : MICCAI ... International Conference on Medical Image Computing and Computer-Assisted Intervention2020
Multimarginal Wasserstein Barycenter for Stain Normalization and Augmentation.
Article in Medical image computing and computer-assisted intervention : MICCAI ... International Conference on Medical Image Computing and Computer-Assisted Intervention, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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Who cites it
4 citing papers in PubMed.
- Computational pathology: A survey review and the way forward.Journal of pathology informatics · 2024Review
- Stain SAN: simultaneous augmentation and normalization for histopathology images.Journal of medical imaging (Bellingham, Wash.) · 2024Article
- Multimodal deep learning to predict prognosis in adult and pediatric brain tumors.Communications medicine · 2023Article
- MixPatch: A New Method for Training Histopathology Image Classifiers.Diagnostics (Basel, Switzerland) · 2022Article
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Authors and funding
3 authors.
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Abstract
Variations in hematoxylin and eosin (H&E) stained images (due to clinical lab protocols, scanners, etc) directly impact the quality and accuracy of clinical diagnosis, and hence it is important to control for these variations for a reliable diagnosis. In this work, we present a new approach based on the multimarginal Wasserstein barycenter to normalize and augment H&E stained images given one or more references. Specifically, we provide a mathematically robust way of naturally incorporating additional images as intermediate references to drive stain normalization and augmentation simultaneously. The presented approach showed superior results quantitatively and qualitatively as compared to state-of-the-art methods for stain normalization. We further validated our stain normalization and augmentations in the nuclei segmentation task on a publicly available dataset, achieving state-of-the-art results against competing approaches.
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Registered trials
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