Evidence map›Paper›PMID 33458680›Full record

ArticleCritical care explorations2021

High-Sensitivity Estimate of the Incidence of New-Onset Atrial Fibrillation in Critically Ill Patients.

William F McIntyre, Emilie P Belley-Côté, Maria E Vadakken, Anand S Rai, Alexandra P Lengyel, Bram Rochwerg, Akash K Bhatnagar, Bishoy Deif, Kevin J Um, Jessica Spence and 5 more

Registry-linked trialOpen access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Critical care explorations, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03552588 (High Sensitivity Estimate of the Incidence of Atrial Fibrillation Occurring Transiently With Stress), which is not on this map. Cited by 9 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 2 pooled it
1.7field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03552588 completednot on this map

High Sensitivity Estimate of the Incidence of Atrial Fibrillation Occurring Transiently With Stress (AFOTS Incidence Study)

TypeobservationalSponsorPopulation Health Research InstituteRan2019 to 2020Enrolled249ConditionsAtrial Fibrillation New OnsetArmsContinuous Electrocardiogram
3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 2 syntheses or guidelines pooled it, 13 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Clinical subtypes and prognosis of new-onset atrial fibrillation in critically ill patients.International journal of cardiology. Cardiovascular risk and prevention · 2026
    Article
  4. Review
  5. Review
  6. Article
  7. Article
  8. Review
  9. COVID-19 and AF: What About the Long Game?JACC. Clinical electrophysiology · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 3 institutions in 1 country.

William F McIntyrePopulation Health Research Institute, McMaster University, Hamilton, ON, Canada.
Emilie P Belley-CôtéPopulation Health Research Institute, McMaster University, Hamilton, ON, Canada.
Maria E VadakkenPopulation Health Research Institute, McMaster University, Hamilton, ON, Canada.
Anand S RaiPopulation Health Research Institute, McMaster University, Hamilton, ON, Canada.
Alexandra P LengyelPopulation Health Research Institute, McMaster University, Hamilton, ON, Canada.
Bram RochwergPopulation Health Research Institute, McMaster University, Hamilton, ON, Canada.
Akash K BhatnagarPopulation Health Research Institute, McMaster University, Hamilton, ON, Canada.
Bishoy DeifPopulation Health Research Institute, McMaster University, Hamilton, ON, Canada.
Kevin J UmPopulation Health Research Institute, McMaster University, Hamilton, ON, Canada.
Jessica SpencePopulation Health Research Institute, McMaster University, Hamilton, ON, Canada.
Stuart J ConnollyPopulation Health Research Institute, McMaster University, Hamilton, ON, Canada.
Shrikant I BangdiwalaPopulation Health Research Institute, McMaster University, Hamilton, ON, Canada.
Purnima Rao-MelaciniPopulation Health Research Institute, McMaster University, Hamilton, ON, Canada.
Jeff S HealeyPopulation Health Research Institute, McMaster University, Hamilton, ON, Canada.
Richard P WhitlockPopulation Health Research Institute, McMaster University, Hamilton, ON, Canada.
McMaster University · CAPopulation Health Research Institute · CAImpact · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

To estimate the incidence of new-onset atrial fibrillation in critically ill patients.

designProspective cohort.

settingMedical-surgical ICU. SUBJECTS: Consecutive patients without a history of atrial fibrillation but with atrial fibrillation risk factors.

interventionsElectrocardiogram patch monitor until discharge from hospital or up to 14 days. MEASUREMENTS AND MAIN

resultsA total of 249 participants (median age of 71 yr [interquartile range] 64-78 yr; 35% female) completed the study protocol of which 158 (64%) were admitted to ICU for medical illness, 78 (31%) following noncardiac surgery, and 13 (5%) with trauma. Median Acute Physiology and Chronic Health Evaluation II score was 16 (interquartile range, 12-22). Median duration of patch electrocardiogram monitoring, ICU, and hospital lengths of stay were 6 (interquartile range, 3-12), 4 (interquartile range, 2-8), and 11 days (interquartile range, 5-23 d), respectively.Atrial fibrillation ≥ 30 seconds was detected by the patch in 44 participants (17.7%), and three participants (1.2%) had atrial fibrillation detected clinically after patch removal, resulting in an overall atrial fibrillation incidence of 18.9% (95% CI, 14.2-24.3%).Total duration of atrial fibrillation ranged from 53 seconds to the entire monitoring time. The proportion of participants with ≥1 episode(s) of ≥6 minute, ≥1 hour, ≥12 hour and ≥24 hour duration was 14.8%, 13.2%, 7.0%, and 5.3%, respectively. The clinical team recognized only 70% of atrial fibrillation cases that were detected by the electrocardiogram patch.

conclusionsAmong patients admitted to an ICU, the incidence of new-onset atrial fibrillation is approximately one in five, although approximately one-third of cases are not recognized by the clinical team.

Indexed as

atrial fibrillationcontinuous monitoringcritical illnesspostoperativesecondary

Identifiers

PMID33458680
PMCPMC7803666
OpenAlexW3123830081

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.