Evidence map›Paper›PMID 33458668›Full record

ArticleArchives of rheumatology2020

Biomarkers of Cardiovascular Disease in Patients With Ankylosing Spondylitis.

Ümit Sarp, Evren ÜstÜner, Sehim Kutlay, Şebnem Ataman, Sim Kutlay

Open access · diamondAbstract read
In one paragraph

Article in Archives of rheumatology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
0.4field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it, 3 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Ümit SarpDepartment of Physical Medicine and Rehabilitation, Ankara University School of Medicine, Ankara, Turkey.ORCID 0000-0001-8148-979X
Evren ÜstÜnerDepartment of Radiology, Ankara University School of Medicine, Ankara, Turkey.ORCID 0000-0003-0932-1508
Sehim KutlayDepartment of Physical Medicine and Rehabilitation, Ankara University School of Medicine, Ankara, Turkey.ORCID 0000-0002-6869-6070
Şebnem AtamanDepartment of Physical Medicine and Rehabilitation, Ankara University School of Medicine, Ankara, Turkey.ORCID 0000-0003-3570-3825
Sim KutlayDepartment of Nephrology, Ankara University School of Medicine, Ankara, Turkey.ORCID 0000-0001-6385-2129
Ankara University · TR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesThis study aims to evaluate the inflammatory status and clinical and vascular alterations using tonometry and B-mode sonography in patients with ankylosing spondylitis (AS). PATIENTS AND

methodsThe study included 71 AS patients (57 males, 14 females; mean age 40.1±10.8 years; range, 29 to 51 years) without cardiovascular disease and 30 healthy controls (24 males, 6 females; mean age 41.2±9.3 years; range, 32 to 50 years). We evaluated participants' clinical, biological and functional status along with laboratory data and measured both the arterial stiffness using carotid-femoral pulse wave velocity (PWV) measured by applanation tonometry and carotid intima-media thickness (CIMT) as a preclinical atherosclerosis marker.

resultsThe mean disease duration of AS patients was 10.6±4.2 years. CIMT (p=0.03) and PWV (p=0.04) data showed significant differences between AS patients and healthy controls. Multiregression analysis showed that PWV correlated with age (r

conclusionThis study demonstrated an increase in early preclinical atherosclerosis in AS patients without cardiovascular (CV) disease compared to healthy controls. Therefore, screening AS patients with noninvasive methods for atherosclerosis and subclinical vasculopathy would allow us to take primary prevention measures. We found that the major determinant for increased CV risk was the disease duration, while there was no difference between different treatment modalities.

Indexed as

Ankylosing spondylitisarterial stiffnesscardiovascular diseasepulse wave velocity

Identifiers

PMID33458668
PMCPMC7788654
OpenAlexW3041157549

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.