ReviewACS omega2021
An Enumerated Outlook of Intracellular Micropolarity Using Solvatochromic Organic Fluorescent Probes.
Review in ACS omega, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
9 citing papers in PubMed, 34 citations in OpenAlex.
- Biomolecular Condensates, Crowding, and Membranes: The Role of Water Revealed with Advanced Fluorescence Microscopy and Phasor Analysis.Sub-cellular biochemistry · 2026Review
- Rationally Designed Maleimide Dyes for Large Stokes Shifted Solvatochromism and Aggregation-Induced Emission.Journal of fluorescence · 2025Article
- Highly Potent Fluorenone Azine-based ESIPT Active Fluorophores for Cellular Viscosity Detection and Bioimaging Applications.Journal of fluorescence · 2025Article
- Trifluoroacetyl-Substituted D-π-A Fluorophores: Design Strategies for Strong Solvatochromism and Giga Stokes Shifts.Chemistry, an Asian journal · 2025Article
- Spin-scaled double hybrids with long-range correction solve the TD-DFT overestimation problem in BODIPY dyes: benchmarking and experimental validation.RSC advances · 2025Article
- Solvatochromic Sensitivity of BODIPY Probes: A New Tool for Selecting Fluorophores and Polarity Mapping.International journal of molecular sciences · 2023Article
- Monitoring Cell Plasma Membrane Polarity by a NIR Fluorescence Probe with Unexpected Cell Plasma Membrane-Targeting Ability.ACS omega · 2022Article
- Article
- A Fluorogenic Far Red-Emitting Molecular Viscometer for Ascertaining Lysosomal Stress in Live Cells andFrontiers in chemistry · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The spatiotemporal distribution of intracellular physical parameters of a live cell is heterogeneous and complex. Measuring physical properties inside given cellular compartments (organelles) is challenging and important for therapy and diagnostics. The tiny volume of a single cell and even tinier organelles are not accessible by classical measuring devices. The microenvironment inside an organelle vastly controls the outcome of any biochemical and biophysical processes taking place inside it, which is crucial for the overall cellular health. Therefore, it is very important to understand the microenvironmental physical properties inside cellular organelles. Moreover, specific alterations of such microenvironmental properties were observed in the disease condition, making them a diagnostic hallmark. With this high demand, small-molecule organic fluorophores are emerging as the most successful tool due to their small relative size, bioavailability, and ease of functionalization. In this mini-review, the development of micropolarity-sensitive small organic fluorophore with the capability of targeting a specific cellular organelle has been discussed. Here, we have highlighted the strategies of targeting a specific organelle, the micropolarity, and the challenges and prospects of the field.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.