ArticlePhysics and imaging in radiation oncology2018
Comparison of four dimensional computed tomography and magnetic resonance imaging in abdominal radiotherapy planning.
Article in Physics and imaging in radiation oncology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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13 citing papers in PubMed.
- Impact of daily volumetric imaging on target tracking without fiducial markers during robotic treatment of pancreas.Physics in medicine and biology · 2026Article
- Phantom-based assessment of a modified 4D-MRI protocol for abdominal tumor motion tracking: Effects of sequence parameters and modality comparison.Journal of applied clinical medical physics · 2026Article
- 4D-MRI at 0.55T for internal target volume delineation in liver radiation therapy planning.Medical physics · 2025Article
- Enabling in vivo comparisons of different four-dimensional magnetic resonance imaging sequences for radiotherapy guidance using visual biofeedback.Physics and imaging in radiation oncology · 2025Article
- A systematic review of 4D magnetic resonance imaging techniques for abdominal radiotherapy treatment planning.Physics and imaging in radiation oncology · 2024Review
- Impact of different respiratory gating methods on target delineation and a radiotherapy plan for solitary pulmonary tumors.Cancer medicine · 2024Article
- Assessment of interfraction dose variation in pancreas SBRT using daily simulation MR images.Physical and engineering sciences in medicine · 2023Article
- Comparative study of sub-second temporal resolution 4D-MRI and 4D-CT for target motion assessment in a phantom model.Scientific reports · 2023Article
- 4D lung MRI with high-isotropic-resolution using half-spoke (UTE) and full-spoke 3D radial acquisition and temporal compressed sensing reconstruction.Physics in medicine and biology · 2023Article
- Movement assessment of breast and organ-at-risks using free-breathing, self-gating 4D magnetic resonance imaging workflow for breast cancer radiation therapy.Physics and imaging in radiation oncology · 2022Article
- Target motion management in breast cancer radiation therapy.Radiology and oncology · 2021Review
- Experimental evaluation of four-dimensional Magnetic Resonance Imaging for radiotherapy planning of lung cancer.Physics and imaging in radiation oncology · 2021Article
- Imaging science and development in modern high-precision radiotherapy.Physics and imaging in radiation oncology · 2019Article
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9 authors.
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Abstract
background and purposeFour-dimensional (4D) computed tomography (CT) is widely used in radiotherapy (RT) planning and remains the current standard for motion evaluation. We assess a 4D magnetic resonance imaging (MRI) sequence in terms of motion and image quality in a phantom, healthy volunteers and patients undergoing RT. MATERIALS AND
methodsThe 4D-MRI sequence is a prototype T1-weighted 3D gradient echo with radial acquisition with self-gating. The accuracy of the 4D-MRI respiratory sorting based method was assessed using a MRI-CT compatible respiratory simulation phantom. In volunteers, abdominal viscera were evaluated for artefact, noise, structure delineation and overall image quality using a previously published four-point scoring system. In patients undergoing abdominal RT, the tumour (or a surrogate) was utilized to assess the range of motion on both 4D-CT and 4D-MRI. Furthermore, imaging quality was evaluated for both 4D-CT and 4D-MRI.
resultsIn phantom studies 4D-MRI demonstrated amplitude of motion error of less than 0.2 mm for five, seven and ten bins. 4D-MRI provided excellent image quality for liver, kidney and pancreas. In patients, the median amplitude of motion seen on 4D-CT and 4D-MRI was 11.2 mm (range 2.8-20.3 mm) and 10.1 mm (range 0.7-20.7 mm) respectively. The median difference in amplitude between 4D-CT and 4D-MRI was -0.6 mm (range -3.4-5.2 mm). 4D-MRI demonstrated superior edge detection (median score 3 versus 1) and overall image quality (median score 2 versus 1) compared to 4D-CT.
conclusionsThe prototype 4D-MRI sequence demonstrated promising results and may be used in abdominal targeting, motion gating, and towards implementing MRI-based adaptive RT.
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