ArticlePhysics and imaging in radiation oncology2018
Feasibility of magnetic resonance imaging-only rectum radiotherapy with a commercial synthetic computed tomography generation solution.
Article in Physics and imaging in radiation oncology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 1 of them a synthesis that pooled it.
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Who cites it
20 citing papers in PubMed, 1 synthesis or guideline pooled it, 30 citations in OpenAlex.
- A systematic literature review: deep learning techniques for synthetic medical image generation and their applications in radiotherapy.Frontiers in radiology · 2024Pooled it
- Dental metal artifacts in magnetic resonance-based synthetic computed tomography for brain radiotherapy: Impact on dose, patient setup, and geometric distortion.Physics and imaging in radiation oncology · 2026Article
- Clinical implementation of deep learning-based synthetic CT for MRI-only volumetric modulated arc therapy in head and neck and pelvic cancer patients.Radiation oncology (London, England) · 2025Article
- 3D Unsupervised deep learning method for magnetic resonance imaging-to-computed tomography synthesis in prostate radiotherapy.Physics and imaging in radiation oncology · 2024Article
- Evaluating a radiotherapy deep learning synthetic CT algorithm for PET-MR attenuation correction in the pelvis.EJNMMI physics · 2024Article
- Computed tomography synthesis from magnetic resonance imaging using cycle Generative Adversarial Networks with multicenter learning.Physics and imaging in radiation oncology · 2023Article
- What Is the Comparative Efficacy of Surgical, Endoscopic, Transanal Resection, and Radiotherapy Modalities in the Treatment of Rectal Cancer?Healthcare (Basel, Switzerland) · 2023Review
- A multi-centric evaluation of self-learning GAN based pseudo-CT generation software for low field pelvic magnetic resonance imaging.Frontiers in oncology · 2023Article
- Head and neck cancer patient positioning using synthetic CT data in MRI-only radiation therapy.Journal of applied clinical medical physics · 2022Article
- Validation of an MRI-only planning workflow for definitive pelvic radiotherapy.Radiation oncology (London, England) · 2022Article
- Comparison of Synthetic Computed Tomography Generation Methods, Incorporating Male and Female Anatomical Differences, for Magnetic Resonance Imaging-Only Definitive Pelvic Radiotherapy.Frontiers in oncology · 2022Article
- The benefit of MR-only radiotherapy treatment planning for anal and rectal cancers: A planning study.Journal of applied clinical medical physics · 2021Article
- Optimisation and validation of an integrated magnetic resonance imaging-only radiotherapy planning solution.Physics and imaging in radiation oncology · 2021Article
- Patient position verification in magnetic-resonance imaging only radiotherapy of anal and rectal cancers.Physics and imaging in radiation oncology · 2021Article
- Evaluation of a commercial synthetic computed tomography generation solution for magnetic resonance imaging-only radiotherapy.Journal of applied clinical medical physics · 2021Article
- Multicentre, deep learning, synthetic-CT generation for ano-rectal MR-only radiotherapy treatment planning.Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology · 2021Article
- Clinical implementation of MRI-based organs-at-risk auto-segmentation with convolutional networks for prostate radiotherapy.Radiation oncology (London, England) · 2020Article
- Imaging science and development in modern high-precision radiotherapy.Physics and imaging in radiation oncology · 2019Article
- The rationale for MR-only treatment planning for external radiotherapy.Clinical and translational radiation oncology · 2019Review
- Assessment of dosimetric and positioning accuracy of a magnetic resonance imaging-only solution for external beam radiotherapy of pelvic anatomy.Physics and imaging in radiation oncology · 2019Article
Corrections and comments
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Authors and funding
6 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
background and purposeSynthetic computed tomography (sCT) images enable magnetic resonance (MR)-based dose calculations. This work investigated whether a commercially available sCT generation solution was suitable for accurate dose calculations and position verification on patients with rectal cancer. MATERIAL AND
methodsFor twenty rectal cancer patients computed tomography (CT) images were rigidly registered to sCT images. Clinical volumetric modulated arc therapy plans were recalculated on registered CT and sCT images. Dose deviations were determined through gamma and voxelwise analysis. The impact on position verification was investigated by identifying differences in translations and rotation between cone-beam CT (CBCT) to CT and CBCT to sCT registrations.
resultsAcross twenty patients, within a threshold of 90% of the prescription dose, a gamma analysis (2%, 2 mm) mean pass rate of 95.2 ± 4.0% (±1
conclusionsAccurate MR-based dose calculations using a commercial sCT generation method were clinically feasible for treatment of rectal cancer patients. The accuracy of position verification was clinically acceptable. However, before clinical implementation future investigations will be performed to determine the origin of the systematic shift.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.