Evidence map›Paper›PMID 33458390›Full record

ArticlePhysics and imaging in radiation oncology2018

In-vivo dosimetric analysis in total skin electron beam therapy.

Khaled Elsayad, Christos Moustakis, Manuela Simonsen, Dagmar Bäcker, Uwe Haverkamp, Hans Theodor Eich

Open access · goldAbstract read
In one paragraph

Article in Physics and imaging in radiation oncology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
1.4field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 26 citations in OpenAlex.

  1. Article
  2. Implementing total skin electron irradiation in radiotherapy: a structured change management approach.Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al] · 2026
    Article
  3. Review
  4. Review
  5. Total skin electron beam therapy.Frontiers in oncology · 2025
    Article
  6. Article
  7. Article
  8. Article
  9. The evolving role of reduced-dose total skin electron beam therapy in skin malignancies: the renaissance of a rare indication.Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al] · 2023
    Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Khaled ElsayadDepartment of Radiation Oncology, University Hospital of Münster, Münster, Germany.
Christos MoustakisDepartment of Radiation Oncology, University Hospital of Münster, Münster, Germany.
Manuela SimonsenDepartment of Radiation Oncology, University Hospital of Münster, Münster, Germany.
Dagmar BäckerDepartment of Radiation Oncology, University Hospital of Münster, Münster, Germany.
Uwe HaverkampDepartment of Radiation Oncology, University Hospital of Münster, Münster, Germany.
Hans Theodor EichDepartment of Radiation Oncology, University Hospital of Münster, Münster, Germany.
University Hospital Münster · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

background and purposeThermoluminescent dosimetry (TLD) is an important element of total skin electron beam therapy (TSEBT). In this study, we compare radiation dose distributions to provide data for dose variation across anatomic sites. MATERIALS AND

methodsRetrospectively collected data on 85 patients with cutaneous lymphoma or leukemia underwent TSEBT were reviewed. Patients were irradiated on two linear accelerators, in one of two positions (standing, n = 77; reclined, n = 8) and 1830 in vivo TLD measurements were obtained for various locations on 76 patients.

resultsThe TLD results showed that the two TSEBT techniques were dosimetrically heterogeneous. At several sites, the dose administered correlated with height, weight, and gender. After the first TLD measurement, fourteen patients (18%) required MU modification, with a mean 10% reduction (range, -25 to +35). Individual TLD results allowed us to customize the boost treatment for each patient. For patients who were evaluated in the standing position, the most common underdosed sites were the axilla, perineum/perianal folds, and soles (each receiving 69%, 20%, and 34% of the prescribed dose, respectively). For patients evaluated in a reclining position, surface dose distribution was more heterogeneous. The sites underdosed most commonly were the axilla and perineum/perianal folds (receiving less than one third of prescribed dose). Significant variables were detected with model building.

conclusionTLD measurements were integral to quality assurance for TSEBT. Dose distribution at several anatomical sites correlated significantly with gender, height, and weight of the treated individual and might be predicted.

Indexed as

Cutaneous lymphomaDose distributionDosimeterLeukemia cutisMycosis fungoidesTotal skin electron beam

Identifiers

PMID33458390
PMCPMC7807580
OpenAlexW2804674772

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.