ArticlePhysics and imaging in radiation oncology2018
Perfusion imaging of colorectal liver metastases treated with bevacizumab and stereotactic body radiotherapy.
Article in Physics and imaging in radiation oncology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
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Who cites it
5 citing papers in PubMed.
- Robust multicentre detection and classification of colorectal liver metastases on CT: application of foundation models.NPJ precision oncology · 2026Article
- DCE-MRI assessment of response to neoadjuvant SABR in early stage breast cancer: Comparisons of single versus three fraction schemes and two different imaging time delays post-SABR.Clinical and translational radiation oncology · 2020Article
- Signal changes in T2-weighted MRI of liver metastases under bevacizumab-A practical imaging biomarker?PloS one · 2020Article
- Imaging science and development in modern high-precision radiotherapy.Physics and imaging in radiation oncology · 2019Article
- A Systematic Review on the Role of the Perfusion Computed Tomography in Abdominal Cancer.Dose-response : a publication of International Hormesis SocietyReview
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Authors and funding
7 authors.
Funding
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Abstract
Stereotactic body radiotherapy (SBRT) and bevacizumab are used in the treatment of colorectal liver metastases. This study prospectively evaluated changes in perfusion of liver metastases in seven patients treated with both bevacizumab and SBRT. Functional imaging using dynamic contrast-enhanced CT perfusion and contrast-enhanced ultrasound were performed at baseline, after bevacizumab, and after SBRT. After bevacizumab, a significant decrease was found in permeability (-28%, p < .05) and blood volume (-47%, p < .05), while SBRT led to a significant reduction in permeability (-22%, p < .05) and blood flow (-37%, p < .05). This study demonstrates that changes in perfusion can be detected after bevacizumab and SBRT.
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